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OBJECTIVE Patients with co-occurring autism spectrum disorders (ASD) and substance use disorder (SUD) require special attention from clinical services. Screening for this co-occurrence is not generally an integral part of routine clinical assessments, and failure to identify and understand this group of patients may contribute to a worsening of their symptoms and/or an increase in drug abuse. T...

Software Effort Estimation process is one the most important process in software project management. The importance of software in our daily lives is increasing with every passing day which has resulted in increase in the complexity of softwares. In order to manage software development projects with varying levels of complexity accurate software effort estimations play a pivotal role. This rese...

Much of the mammalian skeleton is composed of bones that originate from cartilage templates through endochondral ossification. Elucidating the mechanisms that control endochondral bone development is critical for understanding human skeletal diseases, injury response, and aging. Mouse genetic studies in the past 15 years have provided unprecedented insights about molecules regulating chondrocyt...

Since the beginning of software development re-usability has been an important aspect. Applying reusable elements the software does not have to be developed from scratch, proved solutions can shorten the software development life cycle and make applications safer. There are several forms of re-usability like function libraries, class libraries, design patterns, component technologies and enterp...

Measurement in software production is essential for understanding, controlling, and improving the software development process. Past research has emphasized the importance of a disciplined data collection process as a prerequisite for a sound, solid, and useful analysis. Unfortunately, measurement programs often rely on manual data collection and therefore require a considerable effort. For thi...

Early software effort estimation is a hallmark of successful software project management. Building a reliable effort estimation model usually requires historical data. Unfortunately, since the information available at early stages of software development is scarce, it is recommended to use software size metrics as key cost factor of effort estimation. Use Case Points (UCP) is a prominent size m...