Background: Several studies link urinary tract infection (UTI) and bladder cancer. However, the association between cancer muscle invasiveness incidence of UTI is not known Objective: This study aimed to occurrence in severity cancer, specifically a patient admitted Karawang regional hospital, Indonesia. Material Methods: single-center retrospective case control. Data were obtained through medi...

OBJECTIVE Noninvasive biomarkers are used routinely in the clinical management of several cancers but bladder cancer detection and surveillance remains dependent on invasive procedures such as cystoscopy. No validated biomarker currently exists in routine clinical practice other than cytology. Gene-based testing has shown great promise for biomarker profiling and this review addresses the curre...

Bladder cancer occurs after the fifth decade and more frequently in men than in women (sex ratio 2:1 to 3:1). It has been associated mainly with smoking, but also with occupational exposure to carcinogens from aniline dyes, paints, rubber, etc, and chronic irritation of the bladder mucosa due to bladder stones, or schistosomiasis. The main symptom is painless hematuria, which in the adult patie...

INTRODUCTION Bladder calculi account for 5% of all urinary system calculi. They are usually seen in older men and occur because of infravesical obstructions such as prostate hyperplasia, neurogenic bladder, urinary tract infection (UTI), foreign bodies, but anti-incontinence surgery in woman and rarely pregnancy can also be predisposing factors for bladder calculus. Bladder stones could also be...

BACKGROUND Up to 70% of patients with non-muscle-invasive bladder cancer (NMIBC) experience disease recurrence, making it one of the most prevalent cancers in the United States. The purpose of this study was to test the performance of a multiplex urinary biomarker assay for the monitoring of voided urine for recurrent bladder cancer. METHODS This retrospective, multicenter study included a to...

BACKGROUND Urinary Bladder cancer is a life threatening and aggressive disease. This retrospective study was conducted in Baluchistan for assessing the risk factors for urinary bladder cancer. METHOD A questionnaire was developed in order to collect the requisite information about the characteristics like age, drinking habits, smoking history, family history of cancer and others factors. Inte...

PURPOSE The purpose of this study was to identify proteins that are potentially involved in the tumor invasion of bladder cancer. EXPERIMENTAL DESIGN We searched for the candidate proteins by comparing the profiles of secreted proteins among the poorly invasive human bladder carcinoma cell line RT112 and the highly invasive cell line T24. The proteins isolated from cell culture supernatants w...

Transitional cell carcinoma of the urinary bladder is a multifocal disease and the whole bladder mucosa is more or less involved in the neoplastic process. A mapping study of 5 cystectomy specimens was performed, and cell proliferation was evaluated immunohistochemically using anti-proliferating cell nuclear antigen (PCNA) monoclonal antibody. A correlation between the pathological findings and...

The proportion of ail cancers represented by urinary bladder cancer varies greatly wi thin Africa and the Middle East, and the ratio of male to female frequency of occurrence is nearly as variable (Parkin, 1986). ln Egyt, the proportion of bladder cancers among aIl cancers in men is twce that in Zambia, four times that in Zimbabwe and 10 times that in Algeria. Very few formai assessments of the...

The diagnosis of bladder cancer is generally made by cystoscopy and biopsy. Moreover, bladder cancer has a very high frequency of recurrence and therefore requires follow-up cystoscopy, along with urine cytology, as periodic surveillance to identify recurrence early. Cystoscopy is invasive and apt with complications like urine infection which sometimes lead to septicaemia with serious consequen...