Multicellular spheroids are very attractive models in oncology because they mimic the 3D organization of the tumour cells with their microenvironment. We show here using 3 different cell types (mammary TSA/pc, embryonic kidney Hek293 and cervical cancer HeLa), that when the cells are growing as spheroids the frequency of binucleated cells is augmented as occurs in some human tumours.We therefor...

This study describes the characteristics of successful and unsuccessful clinical performance in prelicensure nursing students. Clinical evaluation is an important role of nurse educators; however, many feel uncomfortable with its subjective nature, and commonly used criteria for successful and unsuccessful clinical performance are not available in the literature. Using a qualitative descriptive...

traditional and modern vocabulary instruction techniques have been introduced in the past few decades to improve the learners’ performance in reading comprehension. semantic mapping, which entails drawing learners’ attention to the interrelationships among lexical items through graphic organizers, is claimed to enhance vocabulary learning significantly. however, whether this technique suits all...