نتایج جستجو برای: umbilical cord blood mesenchymal stem cells

تعداد نتایج: 2105083  

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2003
D T Covas J L C Siufi A R L Silva M D Orellana

Bone marrow contains a population of stem cells that can support hematopoiesis and can differentiate into different cell lines including adipocytes, osteocytes, chondrocytes, myocytes, astrocytes, and tenocytes. These cells have been denoted mesenchymal stem cells. In the present study we isolated a cell population derived from the endothelium and subendothelium of the umbilical cord vein which...

Aida Java Zadeh, Ali Shariat Razavi, Mohammad Reza Khojasteh, Sajad Sahab Negah,

Neuroinflammation has a significant role in induce of Multiple sclerosis (MS) many approaches have been used to treat MS, but none of these methods have not been able to fully improve. One of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. Using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuroinfla...

Akbar Vahdati, Hossein Sazegar, Masoud Soleimani, Mohamad hossein Karimi, Negar Azarpira,

Background & Objective: Type1 diabetes is characterized by autoimmune destruction of pancreatic β cells, leading to reduced insulin secretion. Differentiation of mesenchymal stem cells (MSCs) into β-like cells offers new ways of diabetes treatment. MSCs can be insulated from the human umbilical cord tissue and differentiate into insulin-producing cells. Material & Methods: Human um...

Journal: :Vox sanguinis 2008
A Brand P Rebulla C P Engelfriet H W Reesink Y Beguin E Baudoux G Kögler M Ebrahimi G Grazzini A Nanni Costa A Bosi N Sacchi L Lombardini S Pupella L Lecchi E D Calderón Garcidueñas J M van Beckhoven H J C de Wit W E Fibbe E B Zhiburt T Bart M Beksaç C Navarrete F Regan

Cord blood banks are institutions designed to store umbilical cord [3] blood (UCB) stem cells [4]. UCB, a source of hematopoietic stem cells [5] (HSCs), has garnered attention from scientific and medical communities since its first successful use in a hematopoietic stem cell transplant (HSCT) in 1988. The umbilical cord [3] is the lifeline by which the growing fetus [6] is nourished by the moth...

Ali Akbar Pourfathoolah Ardeshir Ghavamzadeh Kamran Alimoghadam Mahin Nikougoftar Nahid Naderi Seyed Mohammad Moazzeni,

Background: Dendritic cells (DCs) are the most potent stimulators of primary T cell responses and play a key role in immune reactions after stem cell transplantation. Very little is known about the cord blood (CB) dendritic cells and their potential involvement in the low incidence and lower severity of acute graft-versus-host disease after CB transplantation.   Objectives: The aim of this stud...

Journal: :Stem cell reviews 2006
Jordan H Perlow

successful cure of the hematological manifestations of Fanconi’s anemia (4), thousands of people worldwide have been beneficiaries of these therapeutic advantages, and to date, nearly 500 umbilical cord blood hematopoietic stem cell transplants occur annually in the United States (5). The vast majority of these hematopoietic transplants occur using publicly banked umbilical cord blood, some uti...

Journal: :Cell medicine 2010
Hongyun Huang Lin Chen Paul Sanberg

Recent advances in cell biology, neural injury and repair, and the progress towards development of neurorestorative interventions are the basis for increased optimism. Based on the complexity of the processes of demyelination and remyelination, degeneration and regeneration, damage and repair, functional loss and recovery, it would be expected that effective therapeutic approaches will require ...

Journal: :iranian journal of immunology 0
nahid naderi immunology department, tarbiat modarres university, tehran, iran ali akbar pourfathoolah immunology department, tarbiat modarres university, tehran, iran mahin nikougoftar iranian blood transfusion organization research center kamran alimoghadam hematology, oncology and bmt research center, tehran university of medical sciences, tehran, iran ardeshir ghavamzadeh hematology, oncology and bmt research center, tehran university of medical sciences, tehran, iran seyed mohammad moazzeni immunology department, tarbiat modarres university, tehran, iran

background: dendritic cells (dcs) are the most potent stimulators of primary t cell responses and play a key role in immune reactions after stem cell transplantation. very little is known about the cord blood (cb) dendritic cells and their potential involvement in the low incidence and lower severity of acute graft-versus-host disease after cb transplantation.   objectives: the aim of this stud...

Journal: :Cell transplantation 2010
R Gonzalez L Griparic M Umana K Burgee V Vargas R Nasrallah F Silva A Patel

There have been various forms of mesenchymal stem cell-like (MSC-like) cells isolated from umbilical cords (UCs). The isolation of umbilical cord lining stem cells (ULSCs) may be of great value for those interested in a possible treatment to several disease/disorders. Unlike umbilical cord blood cells, these cells are unique because they can be expanded to therapeutically relevant numbers and c...

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