PURPOSE This study was conducted to determine the predictive value of clinical, laboratory, and imaging variables for the diagnosis of vesicoureteral reflux in children with their first febrile urinary tract infection. MATERIALS AND METHODS One hundred fifty-three children with their first febrile urinary tract infection were divided into two groups according to the results of voiding cystour...

Alzheimer's disease is characterized by the deposition of amyloid-β as extracellular plaques and hyperphosphorylated tau as intracellular neurofibrillary tangles. Tau pathology characterizes not only Alzheimer's disease, but also many other tauopathies, presenting tau as an attractive therapeutic target. Passive tau immunotherapy has been previously explored; however, because only a small fract...

Cardiovascular disease is a leading cause of death in the Western world. Therefore, detection and quantification of atherosclerotic disease is of paramount importance to monitor treatment and possible prevention of acute events. Vascular ultrasound is an excellent technique to assess the geometry of vessel walls and plaques. The high temporal as well as spatial resolution allows quantification ...

This paper describes a high resolution freehand 3D ultrasound system, whose accuracy surpasses that of previously documented systems. Such accuracy is achieved through a series of novel system design and calibration techniques. The accuracy is quantified using a purpose-built, tissue-mimicking phantom, designed to create idealised in vivo scanning conditions. The paper includes a thorough discu...

OBJECTIVE To evaluate the effectiveness of routine ultrasound scanning at 19 weeks' gestation in an unselected population in terms of accuracy of detection of fetal structural abnormality and the effect on obstetric and neonatal care. DESIGN Prospective study over four years. Scans performed by radiographers with overall supervision by a radiologist. SETTING Ultrasound department of distric...

Deep venous thrombosis of the lower extremity poses a diagnostic challenge. Clinical signs and symptoms are often misleading, and sensitive and specific tests are essential for diagnosis. The cost, patient discomfort and risk of morbidity associated with contrast venography have led to the development of noninvasive diagnostic techniques such as Doppler ultrasound, impedance plethysmography and...

It is well known that hydroxyl radicals are generated by ultrasound in water. This study with an electron spin resonance spin-trapping technique showed that hydroxyl radical generation was positively correlated with ultrasound duration and water temperature. The clear fungicidal action against Trichophyton spp. evident by studying cultured cells and the degradation of cytoplasmic and surface st...

Ultrasound current source density imaging (UCSDI) potentially transforms conventional electrical mapping of excitable organs, such as the brain and heart. For this study, we demonstrate volume imaging of a time-varying current field by scanning a focused ultrasound beam and detecting the acoustoelectric (AE) interaction signal. A pair of electrodes produced an alternating current distribution i...

Ninety one patients with urinary tract abnormalities diagnosed before birth were reviewed. Diagnoses based on prenatal and postnatal ultrasound scans alone were compared with the final diagnoses after full urological investigations, with operative or necropsy confirmation in 79 cases. The results confirmed that ultrasound examination before birth usually detects nonspecific abnormalities and al...

We introduce a mathematical model for ultrasound modulated optical tomography and present a simple reconstruction scheme for recovering the spatially varying optical absorption coefficient from scanning measurements with narrowly focused ultrasound signals. Computational results for this model show that the reconstruction of sharp features of the absorption coefficient is possible. A formal lin...