BACKGROUND AND AIMS Many clinicians, patients and patient advocacy groups believe stress to have a causal role in inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. However, this is not corroborated by clear epidemiological research evidence. We investigated the association between work-related stress and incident Crohn's disease and ulcerative colitis using individual...

Aim: To determine the relation between the disease activity of ulcerative colitis and mean platelet volume (MPV) and to evaluate the clinical usage of a more simple and easier determinant. Method: Complete blood count, C-reactive protein (CRP), erythrocyte sedimentation ratio (ESR), serum albumine and prothrombine time were measured in a total of 41 ulcerative colitis patients. The clinic, path...

Background: Appendicectomy reduces the risk of having ulcerative colitis. However, its effect on the natural history of ulcerative colitis remains uncertain. Aim: To determine whether appendicectomy reduces the overall severity of ulcerative colitis. Patients and methods: Appendicectomy status and smoking habits were specified by direct interview in 638 patients seen consecutively between 1997 ...

BACKGROUND AND AIMS In children with ulcerative colitis, data on temporal colectomy trends and in-hospital post-colectomy complications are limited. Thus, we evaluated time trends in colectomy rates and post-colectomy complications in children with ulcerative colitis. METHODS We identified all children (≤18years) with a diagnosis code of ulcerative colitis (ICD-9: 556.X) and a procedure code ...

Utilising the population based data resources of the Rochester Epidemiology Project, we determined the incidence and prevalence of chronic ulcerative colitis among Rochester, Minnesota, residents over the 20 year period, 1960-79. One hundred and thirty eight cases met diagnostic and residency criteria, for an overall age, and sex adjusted chronic ulcerative colitis incidence rate of 15.0 per 10...

OBJECTIVE Large-scale clinical studies have shown that ulcerative colities were related with colorectal cancer. In this study, animal model was established by AOM/DSS method to explore the activation of IL-6-STAT3-SOCS3 signaling pathway and the expression of pathway-related proteins in ulcerative colitis carcinogenesis, in order to lay a foundation for exploring the regulation mechanism of IL-...

BACKGROUND Patients with inflammatory bowel disease are at risk of developing metabolic bone disease. AIMS To compare bone mineral density in patients with Crohn's disease with patients with ulcerative colitis and healthy subjects, and to evaluate possible risk factors for bone loss in inflammatory bowel disease. PATIENTS 60 patients with Crohn's disease, 60 with ulcerative colitis, and 60 ...

BACKGROUND Appendicectomy reduces the risk of having ulcerative colitis. However, its effect on the natural history of ulcerative colitis remains uncertain. AIM To determine whether appendicectomy reduces the overall severity of ulcerative colitis. PATIENTS AND METHODS Appendicectomy status and smoking habits were specified by direct interview in 638 patients seen consecutively between 1997...

The purpose of these studies is to determine the colonic myoelectrical and contractile response after eating a 1000 calorie meal in patients with active ulcerative colitis. During fasting, slow waves are identifiable significantly more in patients with ulcerative colitis than in normal subjects (p < 0 . 01). The predominant slow wave frequency is 6 . 1 +/- 0 . 2 cycles/min, which is similar to ...

BACKGROUND Ulcerative colitis disease activity indices have not been formally validated. AIM To analise quantitatively the psychometric and performance validity of two non-endoscopic indices for ulcerative colitis, the Simple Clinical Colitis Activity Index and the Seo Index. METHODS In 66 patients with ulcerative colitis, the measurement of disease activity was repeated with the two non-en...