BACKGROUND AND AIMS Several conditions that delay gastrointestinal transit are associated with unconjugated hyperbilirubinaemia. We hypothesised that the gastrointestinal transit time is directly related to plasma unconjugated bilirubin (UCB) concentrations, and that this relationship can be used to develop a new therapeutic strategy for severe unconjugated hyperbilirubinaemia in the Gunn rat m...

We consider a learner’s problem of acquiring data dynamically for training a regression model, where the training data are collected from strategic data sources. A fundamental challenge is to incentivize data holders to exert effort to improve the quality of their reported data, despite that the quality is not directly verifiable by the learner. In this work, we study a dynamic data acquisition...

Recipients of umbilical cord blood (UCB) transplantation (UCBT) face a high risk of morbidity and mortality related to opportunistic infections (OI) and leukemic relapse. To understand the molecular basis of these UCBT-related complications, the characteristics of UCB-derived antigen-specific CD8(+) T cells were examined in a group of pediatric UCBT recipients. Compared with the UCB graft inocu...

Umbilical cord blood (UCB) is being increasingly used for hematopoietic stem cell transplantation and has been associated with a reduced incidence of severe graft-versus-host disease (GVHD). To further investigate the relative merits of unrelated donor UCB versus bone marrow (BM), a matched-pair analysis comparing the outcomes of recipients of 0 to 3 human leukocyte antigen (HLA)–mismatched UCB...

Fetal stem cells isolated from umbilical cord blood (UCB) possess a great capacity for proliferation and differentiation and serve as a valuable model system to study gene regulation. Expanded knowledge of the molecular control of hemoglobin synthesis will provide a basis for rational design of therapies for β-hemoglobinopathies. Transcriptome data are available for erythroid progenitors derive...

cold stress is one of the important factors which will reduce crop yield and fruit production in world. Early spring cooling and freezing weather is mostly. Possible this may considerable damage pistachio productions and farmer will lose most of their profit. Therefore study which show how pistachio plant cope freezing weather is valuable and important. The special role of amino acid in plant r...

Many problems, such as cognitive radio, parameter control of a scanning tunnelling microscope or internet advertisement, can be modelled as non-stationary bandit problems where the distributions of rewards changes abruptly at unknown time instants. In this paper, we analyze two algorithms designed for solving this issue: discounted UCB (D-UCB) and sliding-window UCB (SW-UCB). We establish an up...

Umbilical cord blood (UCB) is a source of the rare but precious primitive hematopoietic stem cells (HSC) and progenitor cells that can reconstitute the hematopoietic system in patients with malignant and nonmalignant disorders treated with myeloablative therapy. UCB cells possess an enhanced capacity for progenitor cell proliferation and self-renewal in vitro. UCB is usually discarded, and it e...

Xylella fastidiosa (Xf) is the causative agent of Pierce’s Disease (PD). Collectively, a team of researchers (Lindow, Dandekar, Labavitch/Powell and Gilchrist) has identified or constructed and advanced the evaluation of five (Table 1) novel genes (DNA constructs) that, when engineered into grapevines, suppress symptoms of PD by reducing the titer of Xf in the plant, reducing its systemic sprea...