نتایج جستجو برای: ubiquinol 10
تعداد نتایج: 1016897 فیلتر نتایج به سال:
Coenzyme Q10 (CoQ10) is a lipid-soluble component from benzoquinones. The oxidized form of ubiquinone, and the reduced ubiquinol. As well to its endogenous synthesis, also included in diet. Dietary sources CoQ10 are meat, poultry, fish, oil, nuts. has an important role energy metabolism mitochondria. It protects phospholipids, proteins, DNA oxidative damage membrane. stated that several positiv...
The respiratory chain in the inner mitochondrial membrane contains three large multi-enzyme complexes that together establish the proton gradient for ATP synthesis, and assemble into a supercomplex. A 19-Å 3D map of the 1.7-MDa amphipol-solubilized supercomplex I(1)III(2)IV(1) from bovine heart obtained by single-particle electron cryo-microscopy reveals an amphipol belt replacing the membrane ...
An arylazido ubiquinone derivative, 2,tdimethoxy5-methyl-6{10-[4-(azid0-2-nitroanilinopropionoxy)]decyl} -1,4-benzoquinone, restores about 60% of the electron transfer activity to ubiquinoneand phospholipid-depleted succinateor ubiquinol-cytochrome c reductases, compared to that restored by 2,3-dimethoxy5-methyl-6-(1O-bromodecyl)-1,4-benzoquinone. The restored activity is fully sensitive to ill...
Mitochondrial oxidative phosphorylation (OXPHOS) is responsible for generating the majority of cellular ATP. Complex III (ubiquinol-cytochrome c oxidoreductase) is the third of five OXPHOS complexes. Complex III assembly relies on the coordinated expression of the mitochondrial and nuclear genomes, with 10 subunits encoded by nuclear DNA and one by mitochondrial DNA (mtDNA). Complex III deficie...
The Unusual Homodimer of a Heme‐Copper Terminal Oxidase Allows Itself to Utilize Two Electron Donors
The heme-copper oxidase superfamily comprises cytochrome c and ubiquinol oxidases. These enzymes catalyze the transfer of electrons from different electron donors onto molecular oxygen. A B-family hyperthermophilic bacterium Aquifex aeolicus was discovered previously to be able use both naphthoquinol as donors. Its mechanism well evolutionary significance are yet unknown. Here we solved its 3.4...
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