Controversy continues as to whether uncontrolled or controlled hemorrhage is the most appropriate for the study of hemorrhagic shock and resuscitation. To appraise differences between these models, we evaluated the relationship between blood volume loss and blood pressure in controlled versus uncontrolled hemorrhage. Anesthetized, instrumented, immature female pigs (40 kg) were assigned to one ...

B = Einstein absorption coefficient E = total energy, P ns s s es 12 uiui , J=m g = electronic state degeneracy H = shape factor, = , dimensionless h = specific enthalpy, J=kg h = Planck’s constant h = enthalpy of formation, J=kg I = radiative intensity,W=cm-sr J = diffusive mass flux, kg=m s Le = Lewis number, dimensionless M = Mach number, dimensionless n = number density, m 3 p = pressure, P...

We consider the one-dimensional bin packing problem with unit-capacity bins and item sizes chosen according to the discrete uniform distribution Ufj; kg, 1 < j k; where each item size in f1=k; 2=k; : : :; j=kg has probability 1=j of being chosen. Note that for xed j; k as m ! 1 the discrete distributions Ufmj; mkg approach the continuous distribution U(0; j=k], where the item sizes are chosen u...

We consider the one-dimensional bin packing problem with unit-capacity bins and item sizes chosen according to the discrete uniform distribution Ufj; kg, 1 < j k; where each item size in f1=k; 2=k; : : : ; j=kg has probability 1=j of being chosen. Note that for xed j; k as m ! 1 the discrete distributions Ufmj; mkg approach the continuous distribution U(0; j=k], where the item sizes are chosen ...

traumatic brain injury (tbi) is one of the most common neurological diseases with no definite treatment. erythropoietin (epo) and progesterone (prog) have been shown to have neuroprotective effects in different types of experimental brain injury models. this study was designed to determine the effect of epo, prog and combination of epo/prog on neurological outcome after traumatic brain injury. ...

BACKGROUND In general, the dose requirement and complications of propofol are lower when used in the diluted form than in the undiluted form. The aim of this study was to determine the dose requirement and complications of diluted and undiluted propofol for deep sedation in endoscopic retrograde cholangiopancreatography. METHODS Eighty-six patients were randomly assigned to either group D (di...

We evaluated liposomal amphotericin B (AmBisome; Vestar, San Dimas, CA) administered to 88 immunocompetent patients (56 children) with visceral leishmaniasis (VL) caused by Leishmania infantum. Thirteen patients received 4 mg/kg on days 1-5 and 10 (total dose, 24 mg/kg), and all were cured; 42 received 3 mg/kg on days 1-5 and 10 (18 mg/kg), and 41 were cured; 32 received 3 mg/kg on days 1-4 and...

BACKGROUND Sunitinib, a tyrosine kinase inhibitor to treat GIST and mRCC may interact with paracetamol as both undergo P450 mediated biotransformation and P-glycoprotein transport. This study evaluates the effects of sunitinib-paracetamol coadministration on liver and renal function biomarkers and liver, kidney, brain, heart and spleen histopathology. ICR male mice (n = 6 per group/dose) were a...