نتایج جستجو برای: tubular syndrome
تعداد نتایج: 649657 فیلتر نتایج به سال:
Inherited tubular disorders associated with metabolic alkalosis are caused by several gene mutations encoding different tubular transporters responsible for NaCl renal handling. Body volume and renin-angiotensin-aldosterone system status are determined by NaCl reabsorption in the distal nephron. Two common hallmarks in affected individuals: hypokalemia and normal / high blood pressure, support ...
I NCREASE in urinary volume and disappearance of edema following administration of adrenocorticotrophic hormone (ACTH) and cortisone to patients suffering from the nephrotic syndrome have been reported by several investigators.1-6 This therapeutic approach to edema does not rule out the primary renal nature of the nephrotic syndrome. In spite of the remarkable diuretic effect of such compounds ...
Multiple rodent models have been used to study diabetic kidney disease (DKD). The purpose of the present study was to compare models of diabetes and obesity-induced metabolic syndrome and determine differences in renal outcomes. C57BL/6 male mice were fed either normal chow or high fat diet (HFD). At postnatal week 8, chow-fed mice were randomly assigned to low-dose streptozotocin (STZ, 55 mg/k...
Fibrotic degeneration was examined in the kidneys of ICR-derived glomerulonephritis (ICGN) mice, a novel inbred mouse line with a hereditary nephrotic syndrome of unknown etiology considered to be a good model of human idiopathic nephrotic syndrome. In the present study, we histochemically revealed changes in accumulation of extracellular matrix (ECM) components and in localization of integrins...
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