We used sub-micron metal rod decorated surfaces, 'nano-lawn' structures, as a substrate to study cell-to-cell and cell-to-surface interactions of primary murine astrocytes. These cells form thin membranous tubes with diameters of less than 100 nm and a length of several microns, which make contact to neighboring cells and the substrate during differentiation. While membrane protrusions grow on ...

Differentiation antigens of T and B lymphocytes were sought in human fetal and adult kidney tissues with monoclonal antibodies by indirect immunofluorescence. Antibodies that identify B cells (BA-1 and anti-B1) and leukemia-associated antigens (BA-2, BA-3, and J5) reacted with renal glomerular and tubular epithelium at characteristic stages of nephron development. BA-1 and BA-2 identified primi...

L-14, a dimeric lactose-binding lectin with subunits of 14 kD, is expressed in a wide range of vertebrate tissues. Several functions have been postulated for this lectin, but definitive evidence for a specific biological role has been elusive. In muscle, L-14 is secreted during differentiation and accumulates with laminin in basement membrane surrounding each myofiber. Here we present evidence ...

Endometrial stromal sarcomas account for 0.25% of all uterine malignancies. These tumours were originally divided into low grade and high grade stromal sarcomas, but the recent World Health Organisation classification (2003) recognises low grade stromal sarcoma and undifferentiated endometrial sarcoma. Low grade sarcomas may exhibit other forms of differentiation, including smooth muscle and se...

Vascular tissue engineering aims to restore blood flow by seeding artificial tubular scaffolds with endothelial and smooth muscle cells, thus creating bioartificial blood vessels. Herein, the progenitors of smooth muscle and endothelial cells hold great promise because they efficiently differentiate and harbor longevity. In this review, we describe a novel tissue engineering approach that uses ...

background : the cause of death is difficult to interpret in a road-traffic accident (rta) victim, because multiple injuries make it difficult to decide on the most fatal lesion, particularly when death is delayed by prompt medical intervention; and secondary haemorrhage, renal failure, fat embolism, systemic infections, myocardial or cerebral infarction – all comes under the potential differen...

to find if some indices have predictive value for renal complications. we conducted a cross sectional and included 80 patients with the age ranged 5-17 years, all with the proven diagnosis of β-thalassemia major. a urine and 5 ml of blood sample were obtained from all of the cases. biochemical indices such as serum levels of creatinine, na, mg, hb, and ferritin and also urine levels of na, mg, ...

in the present study, the effect of core on shear lag phenomenon in tubular structures is investigated. three different tubular structure models including model without core, model with central core and model with central core but eliminated in last 15 stories have been analyzed. a shear lag index is defined for evaluating these models. from examination of the results, the effective influence o...

in this paper, optimization and control of a tubular reactor for thermal bulk post-polymerization of styrene have been investigated. by using the reactor mathematical model, static and dynamic simulations are carried out. based on an objective function including polymer conversion and polydispersity, reactor optimal temperature profile has been obtained. in the absence of model mismatch, desire...

In developing organs, epithelial tissue structures are mostly developed by the perinatal period. However, it is unknown whether epithelial cells are already functionally mature and whether they are fixed in their lineage. Here we show that epithelial cells alter their plasticity during postnatal development by examining the differentiation potential of epithelial cell adhesion molecule (EpCAM)(...