نتایج جستجو برای: triple therapy regimen
تعداد نتایج: 726117 فیلتر نتایج به سال:
Telaprevir, a non-structural (NS)3/4A protease inhibitor, is a direct-acting antiviral drug that inhibits viral replication. Triple therapy with telaprevir, pegylated interferon, and ribavirin is a standard therapeutic regimen for patients with genotype 1b chronic hepatitis C virus (HCV) infection and a high viral load. Several factors, including mutations in the NS5A gene, are important predic...
Children with acute lymphoblastic leukemia (ALL) who have completed 2.5 to 3 years of initial chemotherapy have an off-therapy relapse rate of approximately 20%. In an attempt to improve the survival of children with a late bone marrow (BM) relapse (ie, occurring greater than 6 months after cessation of primary therapy), the Pediatric Oncology Group designed a randomized study to compare the ef...
The optimal regimen of the anticoagulant and antiplatelet therapies in patients with atrial fibrillation who have had a coronary stent is unclear. It is well recognized that "triple therapy" with aspirin, clopidogrel, and warfarin is associated with an increased risk of bleeding. National guidelines have not made specific recommendations, given the lack of adequate data. In choosing the best an...
A triple therapy based on a proton pump inhibitor (PPI), amoxicillin (AMPC), and clarithromycin (CAM) is recommended as a first-line therapy for Helicobacter pylori (H. pylori) eradication and is widely used in Japan. However, a decline in eradication rate associated with an increase in prevalence of CAM resistance is viewed as a problem. We investigated CAM resistance and eradication rates ove...
*Corresponding Author: Fariba Seighali MD; Assistant Professor of Pediatric Gastroenterology, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences & Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran-Iran Mailing Address: Valiasr Hospital, Imam Khomeini Hospital Complex, Keshavarz Blvd. TehranIran Tel: +98 ...
Background Although it has been shown to be superior to simple antithrombotic drug therapy, most patients are unable to receive timely percutaneous coronary intervention (PCI) and are treated with conventional triple antithrombotic therapy (aspirin, clopidogrel, low-molecular-weight heparin). Here, we evaluate the efficacy and safety of adding low-dose tirofiban to this regimen. Methods A tot...
A number of pharmacological agents have been the focus of clinical trials over the past years. Although no single pharmacological agent is recommended by current guidelines, preliminary negative findings regarding the safety of a triple therapy regimen consisting of prednisone, azathioprine and N-acetylcysteine have raised the question of whether it is no longer a treatment option. More recent ...
Experimental targeted treatments for neoadjuvant chemotherapy for triple-negative breast cancer are currently underway, and a current challenge is predicting which patients will respond to these therapies. In this study, we use data from dynamic contrast-enhanced MRI (DCE-MRI) images to predict whether patients with triple negative breast cancer will respond to an experimental neoadjuvant chemo...
BACKGROUND Hematologic changes that occur with HIV infection and antiretroviral therapy may impact the quality of life of patients and have been associated with morbidity and mortality. The management of anemia and neutropenia has improved survival in persons with HIV. OBJECTIVES This meta-analysis was performed to assess the changes in hemoglobin (Hb) levels and neutrophil counts that occur ...
Abdominal tuberculosis (TB) is a rare but well-documented cause of faecal peritonitis, occasionally occurring in cases where the diagnosis has been delayed, thus resulting in progressive disease. Frequently occurring in the ileo-caecal region, it requires commencement of anti-tubercular regimen and can necessitate surgical intervention. We present a rare case of faecal peritonitis in a young im...
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