A 79-year-old hypertensive, diabetic woman with known ischemic heart disease, previously revascularized, was referred to our Cardiology Department because of effort-induced dyspnoea associated with bilateral calf stiffness during a walk at high altitude. A thallium scan with intravenous (i.v.) dipyridamole stress showed a fixed inferior perfusion defect and a reversible perfusion defect in the ...

Management of patients with dilated cardiomyopathy (DCM) and chronic heart failure (HF) remains challenging. There is a need for novel medical therapies independent of the neurohormonal axis that improve cardiac performance. Experimental and preliminary clinical studies have demonstrated that metabolic modulators enhancing myocardial glucose metabolism directly or indirectly by limiting free fa...

dilatation of a segment of the coronary artery to a diameter of at least 1.5 times that of normal adjacent segments.1 It is a well recognized, albeit rare, finding at cardiac catheterization. Clinical Objective: Coronary artery ectasia (CAE) is the abnormal dilatation of a segment of the coronary artery to a diameter of at least 1.5 times that of normal adjacent segments. Symptoms are variable,...