The trigeminal nerve responds to a wide variety of irritants. Trigeminal nerve fibers express several receptors that respond to chemicals, including TRPV1 (vanilloid) receptors, acid-sensing ion channels, P2X (purinergic) receptors, and nicotinic acetylcholine receptors. In order to assess whether TRPV1 plays a role in responses to a broad array of substances, TRPV1 (along with green fluorescen...

BACKGROUND/AIMS Microvascular decompression (MVD) of the trigeminal nerve is a widely accepted treatment for patients with trigeminal neuralgia caused by vascular compression. The neuroendoscope is rapidly becoming a complementary tool in minimally invasive neurosurgery of the ventral anterior skull base. Its adoption in the lateral approach to the posterior fossa has been slower and has been u...

Abstract Attention-deficit hyperactivity disorder (ADHD) with its high prevalence is a growing area of concern and research, whereas exact underlying pathophysiology remains unknown. Behavioral therapy multiple medications include methylphenidate, atomoxetine, amphetamines while trigeminal nerve stimulator (TNS) the first medical device in ADHD FDA approval. The aim this article to evaluate lat...

AIMS To evaluate non-auditory toxicity and local control after linear accelerator stereotactic radiosurgery (SRS) for the treatment of vestibular schwannomas. MATERIALS AND METHODS The institutional policy was to use SRS for radiologically progressing vestibular schwannomas. Case notes and plans were retrospectively reviewed for all patients undergoing SRS for vestibular schwannomas between S...

The upper airway (nasal passages, paranasal sinuses, pharynx, and glottis) provides the sentinel portion of human respiratory tract, with combined senses olfaction (cranial nerve I) trigeminal sensation V) signaling quality inspired air. Trigeminal function also complements sense taste (in turn mediated by cranial nerves VII, IX X), participates in genesis aversions. ability stimulation aero-di...

Introduction: Medically resistant trigeminal neuralgia (TN) is a wellsuited pathology to be treated by radiosurgery (RS). A significant percentage (60%-70%) of patients is expected to benefit from the RS treatment. Imaging is crucial to identify the target, though unfortunately in some cases the trigeminal nerve could not be visible even in high field magnetic resonance images (MRI). The aim of...

A necessary requirement for multisensory integration is the convergence of pathways from different senses. The dorsal cochlear nucleus (DCN) receives auditory input directly via the VIIIth nerve and somatosensory input indirectly from the Vth nerve via granule cells. Multisensory integration may occur in DCN cells that receive both trigeminal and auditory nerve input, such as the fusiform cell....

Ossification of the tentorium cerebelli over the trigeminal notch is rare, but it may cause compression of the trigeminal nerve, leading to trigeminal neuralgia (TN). We were unable to find any previously reported cases with radiological evaluation, although we did find one case with surgically proven ossification of the tentorium cerebelli. Here, we present a case of TN caused by tentorial oss...

Trigeminal neuralgia is a neuropathic disease characterized by severe pain that reduces the patient's quality of life. This case report presents Coronavirus Disease 2019 (COVID-19) positive whose only neurological symptom trigeminal neuralgia. A 59-year-old male patient with complaints weakness, joint pain, cough, and respiratory failure was diagnosed COVID-19. The started on COVID-19 treatment...