Objectives . Alkylated derivatives of polyamines are able to block the growth cancer cells due their embedding into polyamine biosynthesis mechanisms. The study aimed synthesize lipophilic norspermine or triethylenetetramine based on formation a C–N bond during opening oxirane ring by primary amines expand number synthetic with antitumor activity. Methods starting compounds—glycidol alcoholate ...

Polyaminocarboxylic acids have widely been used as antidotes in heavy metal intoxication, however their hydrophilic nature renders them to be mostly distributed extracellularly. To facilitate the intracellular delivery of such chelating agent, triethlenetetraamine-hexaacetic acid (TTHA) was encapsulated in small unilamellar vesicles (SUV) or dehydration rehydration vesicles (DRV) and its effect...

This study focuses on the preparation and modification of a thin-film composite (TFC) hollow fiber polyamide membrane fabricated by the interfacial polymerization of Piperazine (PIP) and trimesoyl chloride (TMC) on a porous polysulfone substrate. The effects of triethylenetetramine (TETA) and silica nanoparticles (SiO2) contents in the aqueous phase (as the additives) on the morphology and perf...