The distribution of acyclic and cyclic biphytanediols, which are the putative breakdown products of glycerol dialkyl glycerol tetraethers (GDGTs), was investigated for recent marine sediments from Nankai Trough, offshore Kii Peninsula. The most abundant diol is tricyclic biphytanediol of which relative abundance is in the range from 32 to 46%. The carbon skeleton of the detected tricyclic biphy...

Venlafaxine is a novel, non-tricyclic antidepressant. Venlafaxine imparts its antidepressant effects by inhibiting the neuronal uptake of norepinephrine, serotonin and to a lesser extent, dopamine1. It lacks monoamine oxidase activity and, more importantly, lacks the adverse effect profile of tricyclic antidepressants. Now, there has been the sustained-release preparation of this drug coming in...

An efficient method towards the synthesis of quinoline fused tricyclic compounds involving an intramolecular 1,3-dipolar nitrile oxide cycloaddition reaction utilizing Baylis-Hillman derivatives in good yields has been described for the first time. A highly functionalized tricyclic framework was created by forming two rings and two adjacent stereocentres through the formation of two N-C bonds, ...

results of the bromination and dehydrobromination of several angular methylated decalindiones are described. the key reaction, base-induced cyclization of the monobromo keto ester (3), and the dibromo ketone (4), leads to the formation of tricyclic systems (6) and (9) respectively.

In this paper, we introduce four new types of contractions called in order Kanan-S-type tricyclic contraction, Chattergea-S-type Riech-S-type Cirić-S-type and prove the existence uniqueness for a fixed point each situation.