Fosravuconazole L-lysine ethanolate (F-RVCZ), a ravuconazole prodrug, is newly available agent with high expectations for efficacy in the treatment of onychomycosis. However, clinical data regarding F-RVCZ are limited because drug was launched only Japan 2018. Therefore, we analyzed outcome therapy onychomycosis at outpatient dermatology clinics Japan. We examined 109 patients (68 male, 41 fema...

oncoplastic breast surgery (obs) has gained widespread acceptance during the last two decades as an integral component of breast cancer surgery. obs combines oncological principles of breast cancer surgery with plastic surgery techniques to provide the best cosmetic results without compromising oncological outcome of breast cancer treatment and it has opened up the possibility to perform breast...

OBJECTIVES To study the value of demographic and alcohol-related variables for predicting 24-month treatment outcome in an outpatient setting. METHODS Prospective observational study with 92 alcohol-dependent patients. Assessments were made by personal interviews at the beginning and end of therapy, and at the 24-month follow-up. Univariate and logistic regression analyses were performed. R...

hematopoietic stem cell transplantation (hsct) has been practiced for more than 30 years. hematological malignanciesare the main indications for this treatment. however, its indications in adults are different from children.advances in chemotherapy and target therapy have improved treatment outcome of some of the very high riskcancers, and changed indications of hsct in children. multi-center c...