AIM To compare the effect of combined low-dose transpupillary thermotherapy (TTT) and intravitreal ranibizumab with sham TTT and intravitreal ranibizumab in patients with neovascular age-related macular degeneration (AMD). METHODS A 24-month, double-masked, randomised, active-controlled clinical trial. 100 patients with primary neovascular AMD were randomly assigned (1:1) to receive intravitr...

bean yellow mosaic virus (bymv, potyvirus, potyviridae) causes serious disease in gladiolus spp. in this work, the possibility of obtaining bymv free plant material from virus infected gladiolus corms was studied. thermotherapy, meristem-tip culture and combination of both techniques on infected corms/meristem-tip explants (0.5–1 mm in length) resulted in bymv elimination up to 15.38, 78.04 and...

BACKGROUND Pentavalent antimonials (Sb5) and miltefosine are the first-line drugs for treating cutaneous leishmaniasis in Colombia; however, toxicity and treatment duration negatively impact compliance and cost, justifying an active search for better therapeutic options. We compared the efficacy and safety of thermotherapy and meglumine antimoniate for the treatment of cutaneous leishmaniasis i...

Purpose: W e evaluated the impact of lower energy transurethral microwave thermotherapy on quality of life and quality of sexual function in patients w ith benign prostatic hyperplasia (B PH ). M aterials and Methods: A total of 50 patients with BPH were randomized to receive either lower energy transurethral microwave thermotherapy treatment (Prostasoft 2.0)* or placebo treatment and followed ...

PURPOSE To correlate fundus autofluorescence (FAF) patterns in choroidal melanocytic lesions with changes present on the surface of such lesions, including lipofuscin, hyperpigmentation, drusen, and fibrous metaplasia, and to describe the effect of treatment on FAF. METHODS Retrospective chart review of 23 consecutive patients with choroidal nevi and melanoma who underwent FAF photography. Th...

Purpose: W e evaluated the impact of lower energy transurethral microwave thermotherapy on quality of life and quality of sexual function in patients w ith benign prostatic hyperplasia (B PH ). M aterials and Methods: A total of 50 patients with BPH were randomized to receive either lower energy transurethral microwave thermotherapy treatment (Prostasoft 2.0)* or placebo treatment and followed ...

In this work, we investigate chemo- thermotherapy, a recently clinically-approved post-surgery treatment of non muscle invasive urothelial bladder carcinoma. We developed a mathematical model and numerically simulated the physical processes related to this treatment. The model is based on the conductive Maxwell's equations used to simulate the therapy administration and Convection-Diffusion equ...

PURPOSE To evaluate individual tumor control following chemoreduction for retinoblastoma. METHODS Prospective nonrandomized single-center case series of 457 retinoblastomas managed with six cycles of chemoreduction (vincristine, etoposide, and carboplatin). The tumors were then managed with chemoreduction alone (group A) or chemoreduction combined with thermotherapy (group B), cryotherapy (gr...

This study was designed to investigate the proliferation inhibition and apoptosis-promoting effect under hyperthermia and chemotherapy treatment, at cellular level. Human gastric cancer cell line SGC-7901 was cultivated with 5-fluorouracil at different temperatures. Cell proliferation and apoptosis were determined, and expression of Bcl-2 and HSP70 was measured at different treatments. Cell sur...

Physical therapy consists of fixation, thermotherapy, traction, and physical training. The symptomatic therapy is effective for some low back pain, including pain due to metastasis by malignant tumors. Fixation with a corset or wide canvas band reduces muscle pain in the low back region as curative therapy, but reduces the pain caused by tumors or inflammation as symptomatic therapy. Thermother...