1. Regeneration of a thymus transplant is characterized by hypertrophy and hyperplasia of the reticulum cells, leading to the formation of small and large atypical Hassall bodies during the early stages. 2. Regeneration is usually complete by the 3rd week, when the newly formed lobules show differentiation into cortical and medullary zones, and typical Hassall bodies appear. 3. Typical Hassall'...

Tissues obtained from 34 human renal allografts by biopsy, 1 to 31 months after transplantation, were studied by histologic, immunofluorescence, and immunoferritin techniques. Our purpose was to gain more precise information concerning the localization of immunoglobulins and complement in glomeruli and to describe the associated tubular and vascular changes. 1. Localization of fluorescein-label...

Bioethics, as a branch of philosophy that focuses on questions relative to health and human life, is closely tied to the idea of justice and equality. As such, in understanding the concept of equality in its original sense, that is, in associating it to the idea to treat "unequals" (those who are unequal or different, in terms of conditions or circumstances) unequally (differentially), in ...

Background. The outcome of patients undergoing a single-lung transplant in the setting of an aborted bilateral lung transplant is unclear. Methods. A retrospective review of single lung transplants at an institutional program. Results. Of the 543 lung transplants performed over the last 10 years, 31 (5.7%) were single-lung transplants. Nineteen of 31 (61%) were planned single-lung transplants, ...

We previously established a novel method for nuclear transfer in medaka (Oryzias latipes) using non-enucleated, diploidized eggs as recipients for adult somatic cell nuclei. Here we report the first attempt to apply this method to another fish species. To examine suitability of using non-enucleated eggs as recipients for nuclear transfer in the zebrafish (Danio rerio), we transferred blastula c...

The first kidney transplant in Iran was performed in 1967, and this was the first organ transplant in countries that are current members of the Middle East Society for Organ Transplantation. In 1988, in response to the long waiting list at the Iranian Ministry of Health for kidney transplant, a state-regulated living-unrelated donor kidney transplant program was adopted. By 1999, the kidney tra...

As of December 2010, more than 35,000 pancreas transplants were reported to the International Pancreas Transplant Registry and nearly 9,000 to the Collaborative Transplant Study databases [1,2]. Pancreas transplantation in diabetic patients is divided into 3 major categories; those performed simultaneously with a kidney (SPK) transplant, usually from a deceased donor; those performed after a su...

PURPOSE Keratoconus is characterized by corneal ectasia and irregular astigmatism, which can lead to diminished vision and corneal scarring. Approximately 10-20% of patients with keratoconus eventually require a corneal transplant. Corneal cross-linking (CXL) is a relatively new treatment that may help prevent the need for corneal transplantation. Here, we investigated whether the introduction ...

Ovarian transplantation is one of the key approaches to restoring fertility in women who became menopausal as a result of cancer treatments. A major limitation of human ovarian transplants is massive follicular loss during revascularization. Here we investigated whether sphingosine-1-phosphate or its receptor agonists could enhance neoangiogenesis and follicle survival in ovarian transplants in...