We present the first case report of a labyrinthine artery aneurysm masquerading as an internal auditory canal tumor. A 72-year-old woman presented with sudden onset right facial paralysis, facial pain, hearing loss, and vertigo. She demonstrated dense right-sided facial paralysis involving all branches of the facial nerve, left beating horizontal nystagmus, and anacusis of the right ear. Magnet...

In this study we evaluate the postoperative facial nerve function after vestibular schwannoma (VS) surgery and analyze the factors that cause it. We included 97 consecutive patients undergoing surgical excision of sporadic unilateral VS. Patient and tumor characteristics, surgical approaches, facial nerve function, extent of tumor removal, perioperative complications are all analyzed through st...

Vestibular schwannomas are the most common neoplasms of the cerebellopontine angle, making up 6-8% percent of all intracranial growths. Though these tumors cause sensorineural hearing loss in up to 95% of affected individuals, the molecular mechanisms underlying this hearing loss remain elusive. This article outlines the steps established in our laboratory to facilitate the collection and proce...

OBJECTIVES/HYPOTHESIS To describe the clinical presentation of peripheral facial palsy caused by neoplastic meningitis. STUDY DESIGN Retrospective case series. METHODS Retrospective review, including accompanying symptoms and magnetic resonance imaging (MRI) findings. RESULTS Between January and December 2011, six patients were diagnosed with peripheral facial palsy caused by neoplastic m...

OBJECTIVE To locate components and target proteins of relevance for the cAMP and cGMP signaling networks including cAMP and cGMP phosphodiesterases (PDEs), salt-inducible kinases (SIKs), subunits of Na+, K+-ATPases, and aquaporins (AQPs) in the human saccule. METHODS The human saccule was dissected out during the removal of vestibular schwannoma via the translabyrinthine approach and immediat...

OBJECTIVES To find the main cause of facial nerve dysfunction in vestibular schwannoma (VS) surgery and review the prognosis of facial function in relation to tumor size, preoperative facial function and surgical approach. METHODS We reviewed the surgical outcome of 134 patients with VS treated in our department between 1994 and 2008. All patients included in the study had postoperative facia...

Surgical treatment of petrous cholesteatoma that involves the petrous pyramid and extends beyond the internal auditory canal is often difficult because of the site and extent of the cholesteatoma. Various problems pertaining to the operation are discussed from our experience with fourteen patients who underwent surgery in our hospital. When accompanied with otorrhea, the middle ear was eradicat...

PURPOSE To identify patterns of enhancement in the internal auditory canal (IAC) on MR studies after removal of an acoustic neuroma, including changes in those patterns with time; to evaluate signal and enhancement of the labyrinth; to differentiate normal postoperative findings from those suggesting residual tumor; and to describe MR hallmarks of surgical approaches. METHODS We reviewed the ...