antiphospholipid antibodies (apla) may be detected in normal pregnancies and also may cause thrombosis, recurrent fetal loss, placental infarction and preeclampsia. in the present study the possible differences in apla titer between healthy pregnant women and preeclampsia cases without history of thrombosis was examined. the apla titer in 50 healthy pregnant women with 50 preeclampsia cases wit...

objective: pseudomonas aeruginosa is the major cause of septicemia and wound infection in burned patients. immunotraphy is the best practical way for prevention and treatment of these infections. flagella as one of the most important bacterial virulence factors has important role in attachment, motility, chemotaxis and tlr-5-dependent immune response so that it propounded as a vaccine candidate...

Background and Objectives: HIV infected patients are at risk for vaccine-preventable infections such as tetanus and diphtheria (Td). In these patients, these antibodies tend to decline faster. Due to the limited data, this study assessed the seroprevalence of tetanus and diphtheria antibodies in HIV infected patients in Tehran, Iran. Materials and Methods: This case-control study was carried o...

Background and Aims: Pertussis is a highly contagious, vaccine-preventable disease. Determination of the seroepidemiology of pertussis makes possible the evaluation of pertussis immunity in a population. In this study, we determined the seroprevalence of Bordetella pertussis IgG antibodies in different age groups in Tehran, Iran. Materials and Methods: Overa...

Background:  Cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) molecules are expressed on T-cells and inhibit their function by inhibiting activation of subsequent T-cell molecular pathways. Blocking of CTLA-4 inhibits the growth of malignant tumor cells. Anti-CTLA-4 monoclonal antibodies activate the immune system against cancer. Due to several advantages of single-chain antibodi...

one hundred sera from children 1 - 6 years of age, representative of a large serum collection, were tested for the prevalence of antibodies against different viruses. hemagglutination-inhibition (hi) antibodies were found in 68% for measles; 61 % for rubella; 75'% for influenza a2/hong kong/68, 16% for influenza b/md./59, 0% for group a arboviruses, 10% for group b arboviruses, 3% for phlebotom...

varicella zoster virus (vzv) is a member of herpes family viruses, which causes varicella (chickenpox) after primary infection and herpes zoster (shingles) because of latent virus reactivation from dorsal root ganglia. generally, prevalence of varicella antibodies increases with age. we aimed to compare the prevalence of anti-vzv antibody in children under seven years old, in order to obtain a ...

two hundred and forty patients, who had undergone vasectomy from 1977 to 1985 and subsequent vasovasostomy ,were studied for the presence of sperm-specific antibodies by using the kibrick's gelatin agglutination test. the number of successful pregnancies and the presence of agglutination were also considered in this survey. sixty-nine pregnancies occurred in total and agglutination was present ...

Rowells syndrome is a rare disease, combining Lupus Erythematosus (LE) and Erythema Multiforme (EM) like lesions with characteristic immunological pattern, including speckled pattern of Antinuclear Antibodies (ANA), positive anti Ro SSA or La SSB antibodies Rheumatoid Factor (RF)