Background. Because of the increased risk of surgery, thyroid nodules causing compression signs and/or hyperthyroidism are concerning during pregnancy. Patients and Methods. Six patients with nontoxic cystic, four with nontoxic solid, and three with overt hyperthyroidism caused by toxic nodules were treated with percutaneous ethanol injection therapy (PEI). An average of 0.68 mL ethanol per 1 m...

Abstract Liver damage is a common problem around the world, and pharmacocorrection of such disease carried out by administration various drugs. Natural synthetic thio-containing compounds are important in this respect. Most these, however, have side effects do not always meet criteria evidence-based medicine. Therefore, search for new drugs with hepatoprotective properties, characterized high e...

Most problematic liver allograft biopsies are obtained more than year after transplantation, due largely to overlapping clinical, serological and histopathological features of native disease recurrence and other potential causes of late allograft dysfunction. More than one insult can be responsible. About 75% of biopsies from long-surviving recipients with abnormal liver function tests/symptoms...

OBJECTIVE The purpose of this study was to investigate the incidence, cause, and influence of the adverse drug reactions (ADRs) associated with long-term intravenous antibiotics in patients with pyogenic spondylitis (PS). METHODS We retrospectively reviewed the medical records of 84 patients with PS who underwent intravenous antibiotic therapy in our hospital from January 2001 to December 201...

Patients chronically abusing ethanol are more susceptible to the hepatotoxic effects of paracetamol. This could be due to an increased activation of the drug to a toxic metabolite or to a decreased capacity to detoxify the toxic metabolite by conjugation with glutathione (GSH). To test these hypotheses paracetamol 2 g was administered to five chronic alcoholics without clinical evidence of alco...

Purpose: To report a case of asymptomatic Wilson’s disease (WD) in which the identification of a Kayser-Fleischer (K-F) ring and its characterization by confocal biomicroscopy led to the diagnosis. Methods: Case report. Results: Confocal biomicroscopy showed clustered, highly reflective, and round foci in Descemet’s membrane, which we believed to be depositions of copper in this patient with as...

BACKGROUND AND OBJECTIVES Staphylococcus aureus (S. aureus) nasal carriage may be responsible for some serious infections in hemodialyzed patients. The main target of this study was to estimate the prevalence of S. aureus nasal carriage in hemodialysis outpatients and medical staff in hemodialysis centers specifically in Fez region. The second target is to identify the risks of colonization, re...

Due to its laxative effects, senna (Cassia angustifolia) has been used frequently in our country and the whole world. We aimed to present a case in which a probable hepatotoxicity and death occurred because of senna used in large quantities for a long time due to its laxative effects. A sixty years old female patient admitted our emergency service with the complaints of weakness, abdominal pain...

AIM OF THE STUDY The aim of the study was to evaluate the effect and severity of liver diseases of different etiologies on the values of three non-invasive fibrosis markers. MATERIAL AND METHODS Serum samples from 65 patients with alcoholic cirrhosis, 31 with non-alcoholic cirrhosis and 32 with toxic hepatitis, were tested. Cirrhotic patients were classified according to the Child-Pugh scale....

Background Exposure to sustained high concentrations of HCFC-123 is known to be hepatotoxic. We report two simultaneous cases of toxic hepatitis related to exposure to 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123), a common refrigerant, at a Korean fire extinguisher manufacturing facility. Case presentation Patients A and B were men aged 21 and 22 years, respectively, with no notable medical ...