نتایج جستجو برای: total serum bilirubin
تعداد نتایج: 1063649 فیلتر نتایج به سال:
We examined serum bilirubin and various liver-function enzymes as possible risk factors for angiographically documented coronary artery disease (CAD). The studies involved a "training" set of 619 men for whom complete data on all risk factors considered were available, and a "test" set of 258 men for whom some risk factor data were not available. In both study groups, the liver enzymes were not...
Effect of Phototherapy on Serum Bilirubin and Ionized Magnesium Level in Hyperbilirubinemic Neonates
Objectives: Jaundice is a main problem in the early neonatal period and it is suggested that there is a positive correlation between plasma ionized Mg levels and severity of hyperbilirubinemia in newborn. The aim of this study is to explore the association and to evaluate and interpret its clinical significance as well as to observe the effect of phototherapy on serum magnesium and bilirubin le...
Site-directed mutagenesis of human serum albumin was used to study the role of various amino acid residues in bilirubin binding. A comparison of thermodynamic, proteolytic, and x-ray crystallographic data from previous studies allowed a small number of amino acid residues in subdomain 2A to be selected as targets for substitution. The following recombinant human serum albumin species were synth...
BACKGROUND AND OBJECTIVE Using light-emitting diodes during conventional phototherapy, it is possible to reduce the distance from light source to infant, thus increasing light irradiance. The objective of this study was to search for a "saturation point" (ie, an irradiation level above which there is no further decrease in total serum bilirubin [TsB]). This was a prospective randomized study pe...
The Du Pont aca “NBIL” test (Du Pont Instruments, Wilmington, DE 19898) also measures bilirubin spectrophotometrically. Figure 2 shows an approximate linear relationship between “apparent” biliburin concentration, as measured with the Bilirubin Stat-Analyzer and the aca NBIL test, vs Liposyn concentration in a neonatal serum sample. This sample without added Liposyn gave identical total bilirub...
Breast-fed infants have higher bilirubin level than formula-fed infants which is of undetermined etiology. The cholestatic effect of cytokines (e.g. IL-1beta, IL-6) is believed to result from the repression of genes that normally mediated the hepatic uptake, metabolism, and biliary excretion of bile salts and bilirubin. The present study aimed to assess the level of interleukin 1beta (IL1beta) ...
Background: Regarding the diagnostic errors of the classic criteria including serum ascites albumin gradient (SAAG), total protein concentration and the adapted Light et al’s criteria in distinguishing transudate versus exudates, we evaluated the ascitic fluid to serum bilirubin ratio as a new criteria in this regard. We also evaluated whether the combination of bilirubin ratio with each of the...
Variation in serum bilirubin is associated with altered cardiovascular disease risk and drug metabolism. We aimed to identify genetic contributors to variability in serum bilirubin levels by combining results from three genome-wide association studies (Framingham heart study, n = 3424; Rotterdam study, n = 3847; Age, Gene, Environment and Susceptibility-Reykjavik, n = 2193). Meta-analysis showe...
BACKGROUND The association between serum bilirubin levels and incident chronic kidney disease (CKD) in the general population is unknown. We aimed to examine the association between serum bilirubin concentration (total, direct, and indirect) and the risk of incident CKD. METHODS AND FINDINGS Longitudinal cohort study of 12,823 Korean male workers 30 to 59 years old without CKD or proteinuria ...
Liver function tests (LFTs) have been reported as independent predictors of non-liver disease-related morbidity and mortality in general population and cancer patients. In this study, we evaluated the relationship between pretreatment serum LFTs and overall survival (OS) in non-metastatic Caucasian breast cancer patients. Seven LFTs, including albumin, alanine aminotransferase, aspartate aminot...
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