The thermal degradation of tyrosine at a residence time of 0.2s was conducted in a tubular flow reactor in flowing N2 and 4% O2 in N2 for a total pyrolysis time of 3min. The fractional pyrolysis technique, in which the same sample was heated continuously at each pyrolysis temperature, was applied. Thermal decomposition of tyrosine between 350 and 550°C yielded predominantly phenolic compounds (...

Skin reactions at the infusion site are a common side effect of continuous subcutaneous insulin infusion therapy. We hypothesized that local skin complications are caused by components of commercial insulin formulations that contain phenol or m-cresol as excipients. The toxic potential of insulin solutions and the mechanisms leading to skin reactions were explored in cultured cells. The toxicit...

BACKGROUND Exposures to environmental phenols and parabens may be harmful, especially in utero. Prior studies have demonstrated high within-person variability of urinary concentrations across pregnancy. OBJECTIVES We sought to measure phenol and paraben biomarker concentrations for the Norwegian Mother and Child Cohort (MoBa) study, assess within-person variability, and investigate any possib...

BACKGROUND The study of phenolic compounds profiles and antioxidative activity in ginseng fruit, leaves, and roots with respect to cultivation years, and has been little reported to date. Hence, this study examined the phenolic compounds profiles and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free-radical-scavenging activities in the fruit, leaves, and roots of Korean ginseng (Panax ginseng Meyer) a...

Natural products from fungi are reported for various anticancer, antioxidant and other biological activities. So in search for novel bioactives from fungi isolated and identified from infected leaves of Rhododendron sp. Thus the isolated fungus was identified as Monochaetia kansensis, was extracted with variety of solvents of increasing polarity such as chloroform, Dichloromethane and ethylacet...

Specific phenol compounds including rhododendrol (RD), a skin-brightening ingredient in cosmetics, are reported to induce leukoderma, inducing a social problem, and the elucidation of mechanism of leukoderma is strongly demanded. This study investigated the relationship among the cytotoxicities of six phenol compounds on B16F10 melanoma cells and HaCaT keratinocytes and generated reactive oxyge...

The sorption of 12 neutral organic compounds (NOCs) contained in mixtures to both hydrophilic mineral surfaces [uncoated, iron (hydr)oxide-coated, and aluminum (hydr)oxide-coated sands] and humic acid-mineral complexes with different fractions of organic carbon, f oc (1⁄4 0:051, 0.119, and 0.221%) was evaluated using batch equilibrium sorption tests. The 12 compounds included six nonpolar NOCs ...

Geranylated hydroquinones and other geranylated compounds isolated from Aplydium species have shown interesting biological activities. This fact has prompted a number of studies where geranylated phenol derivatives have been synthesized in order to assay their bioactivities. In this work, we report the synthesis of a series of new hydrated geranylphenols using two different synthetic approaches...

The development of sensors and biosensors based on copper enzymes and/or copper oxides for phenol sensing is disclosed in this work. The electrochemical properties were studied by cyclic and differential pulse voltammetry using standard solutions of potassium ferrocyanide, phosphate/acetate buffers and representative natural phenols in a wide pH range (3.0 to 9.0). Among the natural phenols her...

In order to determine phenolic compounds in water, we propose a method based on the reaction of phenolic compounds with 4-aminoantipyrine in the presence of peroxodisulfate at pH 10 to form antipyrine dye and the solid-phase extraction of dye with a Varian Bond Elut Plexa cartridge. Dye collected on the cartridge is eluted with acetonitrile and the absorbance is measured at 475 nm. In our exper...