BACKGROUND It is intriguing and imperative that the comparison of the iron preparations in hemodialysis (HD) patients. This study aimed to observe the short-term efficacy of parenteral iron sucrose and ferric chloride in HD patients. MATERIALS AND METHODS This was a consecutive 10-week single-blind study in Taiwan. An intravenous iron supplement of 100 mg/week was administered as an infusion ...

A method is described for measuring the plasma unsaturated iron-binding capacity in the presence of very high concentrations of iron as iron-dextran. The procedure utilizes (59)Fe to label the apotransferrin with subsequent separation of ionic iron from transferrin-bound iron on an ion exchange or Sephadex G.25 column. The unsaturated iron-binding capacity has been measured in rabbits and dogs ...

Background & Aims: The present study deals with an investigation on the effect of iron deficiency anemia and iron supplementation on anemia markers and plasma lipid profiles in pregnant women. Methods: A total of 350 pregnant women were taken and divided into four groups on the basis of haemoglobin levels viz. control (100), mild (100), moderate (100) and severe (50) patients. All the groups we...

utilized iron chelator produced a dramatic effect on survival of patients with thalassemia. However, DFO has poor oral bioavailability and a short half life, necessitating 12 hours of subcutaneous infusion, rendering therapy extremely cumbersome [1]. Deferiprone (DFP), an orally effective iron chelator, reduces total body iron load and is also effective in removing cardiac iron [1-3]. However, ...

\Vitli the technical assistance of Arthur L. Foy T lIE STIMULUS to gastrointestinal absorption of iron remains unknown. Previous work seems to indicate that hepatic iron and total body iron stores are not as important as the rate of iron utilization in regulating iron absorption.’ Stimulation of erythropoiesis by blood letting increases iron utilization. However, following acute phlebotomy ther...

Systemic iron homeostasis depends on the regulated expression of hepcidin, a peptide hormone that negatively regulates iron egress from intestinal cells and macrophages by altering the expression of the cellular iron exporter ferroportin. In doing so, hepcidin can control both the total body iron by modulating intestinal iron absorption as well as promote iron available for erythropoiesis by af...

Sediment from two Georgia Piedmont impoundments and soil from the Georgia Piedmont Bt horizon were incubated with an easily consumable organic carbon substrate in an anaerobic environment to observe iron reduction and phosphorus release. 97% of porewater iron in the Bt horizon soil, 96% of porewater iron in Lake Lanier sediments, and 93% of porewater iron in Lake Oglethorpe sediments was reduce...