The purpose of this study is to assess the effectiveness of faecal management systems in improving survival of patients with extensive burns involving the perineum. All adults with burns of more than 30% total body surface area (TBSA) who were actively treated in our regional burn service between December 2008 and July 2012 were reviewed and compared to an historical cohort of 18 adult patients...

BACKGROUND Childhood mortality is high in low- and middle-income countries. Burns are one of the five leading causes of childhood injury mortality in South Africa (SA). While there is an abundance of literature on burns in the developed world, there are far fewer publications dealing with childhood mortality related to burns in Africa and SA. OBJECTIVE To describe the mortality of children ad...

Toxic epidermal necrolysis (TEN) was first described by Lyell in 1956 (1). It is a rare condition, with 1.2 cases per million per year (2), and is characterized by a diffuse erythematous rash that progresses to desquamation of a large body surface area. Although TEN is in the clinical continuum of erythema multiforme (EM) and Stevens Johnson syndrome (SJS), biopsy shows complete separation of e...

Background. Geriatric patients, usually defined as being 65 years of age or over, now make up about 10% of the major burn population. Main aim. To conduct a prospective study of elderly burn patients, analysing the predictive value of age, gender, total body surface area (TBSA) burned, inhalation trauma, pre-morbid conditions, and mortality. Methods. A 10-year prospective study of burn victims ...

Introduction: We observed serum transthyretin (TTR) constantly maintained low even with adequate nutritional support if the patients’ general conditions are poor. We conducted this study to analyze the change of serum TTR with time from injury in massive burn patient and verify the validity of prediction of clinical outcome with serum TTR of early post-burn period. Methods: From January of 2005...

BACKGROUND Midazolam, a short-acting benzodiazepine, is administered preoperatively and intraoperatively for amnesia and anxiolysis. Subsequently, patients often do not recall events which occurred while they were sedated. Recent studies have also reported retrograde facilitation after midazolam exposure. Posttraumatic stress disorder PTSD is based on memory of a traumatic event. Because of the...

INTRODUCTION Burn injuries are a serious public health problem. In our study we have identified different epidemiological factors based on 10 years of our experience at a burn unit in central India and recommend some strategies to prevent burn injuries. MATERIALS AND METHODS This is a retrospective analysis (2001-2010) of database from burn unit of S.S. Medical College, Rewa, India. RESULTS...

BACKGROUND As a serious clinical problem, severe burn injury disturbs the immune system, resulting in progressive suppression of immune response. TLRs are associated with immune system activation, but the effect of TLRs levels on circulating cDCs of severe burn injury patients has not been fully assessed. MATERIAL AND METHODS Ten patients with total body surface area (TBSA) burned >90% admitted...

Abstract Introduction Current practice for major pediatric burns includes fluid resuscitation using formulas that estimate requirements based on weight and/or body surface area (BSA) along with percent total burn (TBSA). Adult studies have shown these can cause overload in obese patients and increase risk of complications. These findings not been validated patients. This study aims to evaluate ...

Low molecular weight heparin (LMWH) appears to be a promising solution for reducing inflammatory post-burn episodes and results in improved healing. The clinical examination presented here includes patients with burn wounds ranging from 20 to 35% total body surface area (TBSA) who were categorized into two groups, of which one received subcutaneous LMWH treatment (10,000 units/day) and the othe...