A 70-year-old female developed a bacterial ulcer in a previously rejected corneal graft. Cultures identified the pathogen as Enterobacter cloacae. Intensive topical antibiotic therapy arrested the progress of the ulcer, and the epithelial defect healed in one week; there was no resultant stromal thinning. Factors which may have predisposed the cornea to ulceration by this organism of relatively...

BACKGROUND The combination of pulsed dye laser (PDL) and topical propranolol are used with variable effectiveness for the treatment of infantile hemangiomas (IH), particularly for superficial lesions. OBJECTIVE(S) The aim of this study was to investigate whether the therapeutic efficacy of prescribing topical propranolol along with PDL was superior to PDL therapy alone in the treatment of IH....

Topical antibiotics are frequently introduced in therapy by various specialists, e.g., dermatologists-venereologists, ENT specialists, proctologists, ophthalmologists, and others. In dermatology, topical antibiotics are used in the treatment of superficial inflammatory skin lesions, acne and rosacea. These agents are also used in the prevention of inflammatory lesions after surgical and correct...

Thygeson’s superficial punctate keratitis is a subtle, chronic and bilateral condition of the corneal epithelium, typically manifests with acute exacerbations and remissions. The etiology remains uncertain, despite the possibility of viral etiology was suspected. Topical steroid administration is useful in aborting an acute phase; but steroid induced cataract and glaucoma developed on long term...

BACKGROUND Rosacea is a common skin disorder affecting middle-aged and older adults. Many patients mistakenly assume that early rosacea is normally aging skin and are not aware that effective treatments exist to prevent progression to permanent disfiguring skin changes. METHODS The medical literature was reviewed on the pathophysiology, diagnosis, and treatment of rosacea. MEDLINE was searche...

Sir. Nail lichen planus (NLP) is characterized by thinning, longitudinal ridging and distal splitting of the nail plate (1.2). Although mild NLP is usually asymptomatic, deformation of the fingernails is cosmetically distressing. Failure to treat NLP results in nail loss or pennanent nail dystrophy in some cases. Therefore the condition should be treated etïectively in its early stage. NLP is u...

AIM To evaluate the efficacy of topical 5-fluorouracil (5-FU) alone, without concurrent surgery or radiotherapy, for the treatment of conjunctival squamous cell carcinoma. METHODS Eight patients affected by conjunctival squamous cell carcinoma (three recurrent cases, three incompletely excised, and two untreated cases) were treated with 1% 5-FU eye drops. Topical 1% 5-FU was administered four...

purpose: to determine whether adding 2% topical cyclosporine (csa) to local and systemic steroids in treatment of endothelial corneal allograft rejection improves the outcome. methods: a prospective randomized treatment trial was carried out on 40 consecutive corneal graft recipients, presenting with the first episode of endothelial graft rejection in two groups. group one (20 patients) receive...

Objective. To determine the most costeffective treatment for phimosis. Design. The costs of three treatment strategies for treating phimosis were evaluated using a decision-tree analysis. Three therapeutic approaches were considered: circumcision, preputial plasty (the use of plastic surgical techniques to enlarge the preputial opening without removing tissue), and topical therapy with steroids...

When liposomes were initially discovered more than 30 years ago, predictions were largely met with skepticism; however, recent advances have allowed the development of liposomes that are potentially medically useful. Systemic and topical drug delivery by liposomes is possible. Although liposomal amphotericin B, a systemic antifungal agent, is the only medical liposomal product commercially avai...