In the modern times, vesicular system is a well-known carrier for delivery of drugs. They can carry both lipophilic and hydrophilic Proniosomes are vital member novel drug carriers. The present study was aimed to develop prepare Metronidazole Benzoate loaded proniosomes with different ratios cholesterol non-ionic surfactants prolong release on topical administration. By slurry method, about fou...

Tuberous sclerosis complex (TSC) is a genetic multisystem disorder with prominent skin involvement including facial angiofibromas that often appear in early childhood. Here we report the case of a 12-year-old girl with widespread disfiguring facial angiofibromas that were successfully treated with topical rapamycin, a mTOR inhibitor. A sustained remission of skin lesions was documented in detai...

Few case reports have documented the use of topical cidofovir for refractory genital herpes simplex virus (HSV) ulcers in human immunodeficiency virus (HIV) infected patients. This drug formulation lacks a standardized concentration or even a procedural outline as to how it should be compounded. We aim to discuss the utilization of topical cidofovir in addition to presenting a procedural means ...

determining biological equivalence between pioneer and generic products, checking equivalence after change in batch size, detecting changes in components or composition, and checking equivalence after modification of manufacturing equipment or processes. The test method has also been suggested as a possible standard for quality control of topical drug products. We thus established an in vitro d...

psoriasis is an autoimmune and recurrent chronic inflammatory skin disease. about 1-3% of the world wide populations are affected. the characteristic features are hyperprolifration of keratinocytes leading to redness, thickening and scaling of epidermis followed with itching and appearance of the lesions which in most cases bother the patients medically and psychologically. psoriasis is symptom...