نتایج جستجو برای: tongue cancer
تعداد نتایج: 929764 فیلتر نتایج به سال:
Oral tongue cancer is characterized by a high degree of local invasion and a high rate of metastasis to the cervical lymph nodes. Treatment options for this cancer are limited. However, gene therapy has attracted keen interest as a new strategy for refractory cancer. The aim of this study was to examine the efficiency of transfection of the exogenous p27Kip1 gene by electroporation and the anti...
The production of speech includes considerable variability in speech gestures despite our perception of very repeatable sounds. Variability is seen in vocal tract shapes and tongue contours when different speakers produce the same sound. This study asks whether internal tongue motion patterns for a specific sound are similar across subjects, or whether they indicate multiple gestures. There are...
BACKGROUND Evidence suggests the incidence of oral tongue squamous cell carcinoma is increasing in young patients, many who have no history of tobacco use. METHODS We clinically reviewed 89 patients with oral tongue cancer. Exomic sequencing of tumor DNA from 6 nonsmokers was performed and compared to previously sequenced cases. RNA from 20 tumors was evaluated by massively parallel sequencin...
Five patients with tongue carcinoma were treated for 20 days with bleomycin, 15 mg/day, given by one-shot infusion through the superficial temporal artery. Specimens were taken 7, 14, and 20 days after the initial administration for light and electron microscope observations. The first alterations observed were the decrease of electron-dense chromatin clumps in nuclei and, simultaneously, the s...
Oral cancer is characterized by high morbidity and mortality with a predisposition to metastasize to different tissues, including lung, liver, and bone. Despite progress in the understanding of mutational profiles and deregulated pathways in oral cancer, patient survival has not significantly improved over the past decades. Therefore, there is a need to establish in vivo models that recapitulat...
OBJECTIVES The purpose is to provide detailed estimates of population-based incidences of head and neck cancers (HNCs) between 1999 and 2012 in South Korea and to evaluate trends. METHODS Data was reviewed from the Korea National Cancer Incidence Database regarding the incidence of HNCs between 1999 and 2012. Locations that were surveyed included lip, oral tongue, oral cavity, major salivary ...
Background & Aims: White lesions of the oral cavity are important since they can be one of the manifestations of oral cancer. In addition, the most common precancerous lesions of oral cavity are white lesions. The aim of this study was determining the frequency of white lesions and rate of dysplastic changes in patients referring to Oral Pathology Department, Tabriz, Iran. Materials & Methods:...
BACKGROUND Therapy for head and neck cancers has evolved over the past decade, but few detailed analyses of recent developments in survival on the population level have been published. METHODS We use period analysis and modeled period analysis to disclose recent trends in survival in patients with head and neck cancer. Data are derived from the Surveillance, Epidemiology, and End Results limi...
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