It has long been known that certain organic dyes can photosensitize cells, leading to cellular damage or death. Recently, studies were performed on one such dye, Toluidine Blue, to determine the mechanism of its lethal photosensitization of bacteria (M. M. Mathews, J. Bacteriol. 85:322, 1963). These studies showed that the cellular site of the lethal action was the cytoplasmic membrane and its ...

This study aimed to analyze and sum up the clinical diagnostic method of canine lymphoma. Diagnostic methods applied on 4 cases of lymphoma were summarized and studied. Pathological tissue sections and immunohistochemistry were used as the primary diagnostic tools, while blood biochemical analysis, imaging, toluidine blue staining and IgH gene clonal rearrangement detection were used as adjunct...

Background: It is showed that methamphetamine has harmful effects on male reproductive system. The aim of this study was to investigate the effects of methamphetamine administration on testis weight, sperm count, sperm morphology, and chromatin status as well as sperm apoptotis followed by the cytochemical tests in a mouse model. Materials and Methods: Twenty four NMRI male mice were divided in...