BACKGROUND Tissue Microarrays (TMAs) allow researchers to examine hundreds of small tissue samples on a single glass slide. The information held in a single TMA slide may easily involve Gigabytes of data. To benefit from TMA technology, the scientific community needs an open source TMA data exchange specification that will convey all of the data in a TMA experiment in a format that is understan...

BACKGROUND AND OBJECTIVES Thrombotic microangiopathy (TMA) in ANCA-associated vasculitis (AAV) has been mainly reported in isolated case reports. The aim of this study was to analyze clinical and pathologic characteristics and prognosis of patients with renal TMA in ANCA-associated GN in a large cohort of Chinese patients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Clinical and renal histo...

Experiments were conducted to delineate the vascular effector systems that contribute to setting mesenteric vascular tone in swine during the first postnatal month. Terminal mesenteric arteries (TMA), which function as resistance vessels, were studied in vitro with a microvascular perfusion system allowing independent pressure and flow manipulation. When pressure was varied 0-100 mmHg in the ab...

The midgut epithelium of lepidopteran insect larvae contains characteristic goblet cells possessing an apical cavity surrounded by goblet cell apical membrane (GCAM) and guarded from the gut lumen by a valve-like structure. The currently accepted model of active K+ secretion by the midgut of lepidopteran insect larvae locates the major active step at the GCAM, implying that actively transported...

The aim of this study was to evaluate the clinical performance of the Aptima Mycoplasma genitalium transcription-mediated amplification (MG-TMA) CE-marked for in vitro diagnosis (CE-IVD) assay for the detection of Mycoplasma genitalium in male and female clinical samples in comparison with the in-house real-time PCR (in-house PCR) assay routinely used in our laboratory. A total of 1,431 clinica...

When weather or congestion impacts the National Airspace System, multiple different Traffic Management Initiatives can be implemented, sometimes with unintended consequences. One particular perceived inequity that is commonly identified is in the interaction between Ground Delay Programs (GDPs) and time based scheduling of internal departures by the Traffic Management Advisor (TMA) (now operati...

In oncology research, Tissue Microarray (TMA) technology allows for the mass treatment of hundreds of tissue samples and rapid visualisation of molecular targets. Since this technique is relatively new, there are very few dedicated information systems and little formalised knowledge about the technique is available. We therefore intend to set up an integrated system around TMA technology that i...

PURPOSE To derive a mathematical model of TMA+ diffusion across the retina that can be used to estimate the amplitude and kinetics of the light-evoked increase in subretinal hydration and its effect on the concentration of other ions. METHODS All experimental data were obtained in chick retina-pigment epithelium-choroid preparations as described in the accompanying paper. RESULTS Diffusiona...

BACKGROUND Hemolytic anemia with thrombocytopenia and schistocytosis is suggestive of thrombotic thrombocytopenic purpura (TTP). However, these features can occur in the context of vitamin B12 deficiency. AIM To identify simple means of distinguishing between TTP and pseudothrombotic microangiopathies related to vitamin B12 deficiency (pseudo-TMA) at the bedside. DESIGN AND METHODS Retrospe...

OBJECTIVES To comparatively evaluate the extrusive forces and torquing moments on the posterior dentition generated during anterior intrusion with different intrusion techniques in the maxillary and mandibular dental arch. MATERIAL AND METHODS Seven wire specimens were used for each of the following intrusive arches: Utility arch 0.016 x 0.016' Blue Elgiloy, Utility arch 0.017 x 0.025' TMA an...