Terrestrial laser scanning (TLS) is an efficient solution to collect large-scale data. The efficiency can be increased by combining TLS with additional sensors in a TLS-based multi-sensor-system (MSS). The uncertainty of scanned points is not homogenous and depends on many different influencing factors. These include the sensor properties, referencing, scan geometry (e.g., distance and angle of...

Since its introduction in 1994 the Secure Socket Layer (SSL) protocol (later renamed to Transport Layer Security (TLS)) evolved to the de facto standard for securing the transport layer. SSL/TLS can be used for ensuring data confidentiality, integrity and authenticity during transport. A main feature of the protocol is its flexibility. Modes of operation and security aims can easily be configur...

In yeast, the Rad6-Rad18 ubiquitin conjugating enzyme plays a critical role in promoting replication although DNA lesions by translesion synthesis (TLS). In striking contrast, a number of studies have indicated that TLS can occur in the absence of Rad18 in human and other mammalian cells, and also in chicken cells. In this study, we determine the role of Rad18 in TLS that occurs during replicat...

The standard approaches to solving overdetermined linear systems Ax ≈ b construct minimal corrections to the vector b and/or the matrix A such that the corrected system is compatible. In ordinary least squares (LS) the correction is restricted to b, while in data least squares (DLS) it is restricted to A. In scaled total least squares (Scaled TLS) [15], corrections to both b and A are allowed, ...

Tumor lysis syndrome (TLS), a result of rapid cell lysis following tumor therapy, is a well recognized complication during the treatment of rapidly growing tumors. TLS rarely occurs in solid tumors. We present a case report of TLS in a patient with primary retroperitoneal soft tissue sarcoma. TLS occurred in the patient after four days' combinational chemotherapy with cisplatin, adriamycin, and...

Transport Layer Security (TLS) protocol has been developed by the Internet Engineering Task Force (IETF) as the standard protocol for providing security services in the context of E-commerce over the Internet. Thus TLS enabled web servers form the portals through which E-commerce client server interaction takes place. This paper provides an overview of the design and workings of the TLS protoco...

The presented paper revisits the analysis of the total least squares (TLS) problem AX ≈ B with multiple right-hand sides given by Sabine Van Huffel and Joos Vandewalle, in the monograph: The Total Least Squares Problem: Computational Aspects and Analysis, SIAM Publications, Philadelphia 1991. The newly proposed classification is based on properties of the singular value decomposition of the ext...

We developed new vegetation indices utilizing terrestrial laser scanning (TLS) to quantify the three-dimensional spatial configuration of plant communities. These indices leverage the novelty of TLS data and rely on the spatially biased arrangement of a TLS point cloud. We calculated these indices from TLS data acquired within an existing long term manipulation of forest structure in Central Or...

Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative disorder characterized by the loss of motor neurons. Fused in sarcoma/translated in liposarcoma (FUS/TLS) and TAR DNA-binding protein (TDP)-43 are DNA/RNA-binding proteins found to be mutated in sporadic and familial forms of ALS. Ectopic expression of human ALS-causing FUS/TLS mutations in Drosophila caused an accumulation o...

The only Y-family DNA polymerase conserved among all domains of life, DinB and its mammalian ortholog pol kappa, catalyzes proficient bypass of damaged DNA in translesion synthesis (TLS). Y-family DNA polymerases, including DinB, have been implicated in diverse biological phenomena ranging from adaptive mutagenesis in bacteria to several human cancers. Complete TLS requires dNTP insertion oppos...