Commentary VTE is an important complication of major orthopedic surgery. Advances in surgical technique, early ambulation, and early hospital discharge coupled with safer and more effective pharmacologic agents have reduced the risk for symptomatic VTE (DVT or PE). Rates of symptomatic VTE of 15% to 30% after TKR or THR before 1980 have been reduced to 1% to 2% in some recent studies (1, 2) thr...

BACKGROUND There is little scientific evidence to support the usual practice of providing outpatient rehabilitation to patients undergoing total knee replacement surgery (TKR) immediately after discharge from the orthopaedic ward. It is hypothesised that the lack of clinical benefit is due to the low exercise intensity tolerated at this time, with patients still recovering from the effects of m...

Primary arthroplasty may be denied to very elderly patients based upon the perceived outcome and risks associated with surgery. This prospective study compared the outcome, complications, and mortality of total hip (TKR) and total knee replacement (TKR) in a prospectively selected group of patients aged ≥ 80 years with that of a control group aged between 65 and 74 years. There were 171 and 495...

We performed a combined approach to identify suspected allergy to knee arthroplasty (TKR): patch test (PT), lymphocyte transformation test (LTT), histopathology (overall grading; T- and B-lymphocytes, macrophages, and neutrophils), and semiquantitative Real-time-PCR-based periprosthetic inflammatory mediator analysis (IFNγ, TNFα, IL1-β, IL-2, IL-6, IL-8, IL-10, IL17, and TGFβ). We analyzed 25 T...

Cardiac baroreflex function may be assessed from spontaneous fluctuation of systolic arterial pressure (SAP) and R-R interval. In previous studies, time-domain sequence and cross-spectral analysis had been applied to present the baroreflex response of cardiac system. Detrended fluctuation analysis (DFA) is also a promising algorithm to evaluate the fluctuations under various timescales. Thus, w...

This research aims to develop a nursing care model for patients undergoing total knee replacement surgery (TKR) using the models Kemmis and McTaggart (1988) as development guidelines. The study has started from April July 2020 in Operation Department, Loei hospital, Thailand. purposive sampling method been selected with participant nurses (n=50). mixed design used obtain new guidelines patient ...

A high-dose local tranexamic acid has been introduced in total knee arthroplasty for bleeding control. We are not sure about the systemic absorption and side effects. The aim of this study was to evaluate the effect of low dosage of intra-articular tranexamic acid injection combined with 2-hour clamp drain in minimally bleeding computer-assisted surgery total knee replacement (CAS-TKR). A prosp...

BACKGROUND AND PURPOSE Total knee replacement (TKR) is being increasingly performed in elderly patients, yet there is little information on specific requirements and complication rates encountered by this group. We assessed whether elderly patients undergoing TKR had different length of stay, requirements, complication rates, and functional outcomes compared to younger counterparts. PATIENTS ...

INTRODUCTION The number of total hip and total knee replacement procedures performed worldwide has tended to surge in recent years, due to the combination of such factors as the increased life expectancy, improved quality of life, advances in medical technology as well as pre-operative and post-operative patient management.Numerous studies confirm that patients undergoing major orthopaedics pro...

From January 1991 to June 1997, patients undergoing primary elective monolateral or bilateral total knee replacement (TKR) were consecutively enrolled in a prospective, open clinical study on the efficacy and safety of regional prophylaxis with teicoplanin (TEC). Those scheduled for monolateral TKR (115 patients) received 400 mg of TEC in 100 ml of saline as a 5-min infusion into a foot vein of...