Chromosome instability has a pivotal role among the hallmarks of cancer, but its transcriptional counterpart is rarely considered a relevant factor in cell destabilization. To examine transcription instability (TIN), we first devised a metric we named TIN index and used it to evaluate TIN on a dataset containing more than 500 neuroblastoma samples. We found that metastatic tumors from high-risk...

Article history: Received 28 September 2015 Revised 2 December 2015 Accepted in revised form 11 December 2015 Available online 12 December 2015 A three-layer backward propagation (BP)modelwas used to predict the hardness of Ni–TiNnanocoatings fabricated by pulse electrodeposition. The effect of plating parameters, namely, TiN particle concentration, current density, pulse frequency, and duty ra...

Two dimensional nanostructures of group IV elements have attracted a great deal of attention because of their fundamental and technological applications. A graphene-like single layer of tin atoms, commonly called stanene, has recently been predicted to behave like a quantum spin Hall insulator. Here we report the atomic structure, stability and electron transport properties of stanene stabilize...

The movement to eliminate lead (Pb), especially active in Japan and the European Union, has resulted in an increasing use of pure tin (Sn) coatings on leads and other external and internal surfaces of capacitors, resistors, and other passive components. This paper discusses the issues of tin whisker growth with respect to passive components. It also presents both a critical analysis of existing...

pure and antimony doped sno2 thin films have been prepared by the sol-gel dip coating technique on glass substrate using starting material sncl2.2h2o as a host and sbcl3 as a dopant. our experimental results revealed that, the quality of the coated films on the glass depends on process parameters. the effect of annealing temperature, dipping numbers and the dopant concentration on the structura...

We investigated the emission features of tin neutrals in a laser-ablated tin plasma using time and space resolved optical emission spectroscopy. The tin plume was generated by focusing 1064 nm, 10 ns pulses from a Nd : YAG laser on a tin slab target placed in a vacuum chamber. We examined the properties of the tin neutrals at various spatial locations from the target surface and at different la...

Surfaces of medical implants can be enhanced with the favorable properties of titanium-nitride (TiN). In a review of English medical literature, the effects of TiN-coating on orthopaedic implant material in preclinical studies were identified and the influence of these effects on the clinical outcome of TiN-coated orthopaedic implants was explored. The TiN-coating has a positive effect on the b...

The NK homeobox gene tinman (tin) is required for the specification of the cardiac, visceral muscle and somatic muscle progenitors in the early dorsal mesoderm of Drosophila. Like its vertebrate counterpart Nkx2.5, the expression of tin is maintained in cardiac cells during cardiac maturation and differentiation; however, owing to the complete lack of a dorsal vessel in tin mutant embryos, the ...