Monoclonal antibodies were used to examine the immunoglobulin isotypes expressed by B lymphocyte precursors of IgM, IgG, IgA, and IgA2 plasma cells. Plasma-cell differentiation was induced by the addition of pokeweed mitogen to cultures of blood mononuclear cells. Anti-mu, -gamma, -alpha, and -alpha 1 antibodies were used in some experiments to inhibit differentiation of B lymphocytes bearing t...

Although it is usually assumed that all those who commit suicide give some prior indication of their intention to take their own life, there is growing evidence that a small but significant proportion of suicides occur without clear, explicit indicators. It is proposed that these suicides emerge from similar pathways to other suicides but the despair is not expressed so clearly, often being kep...

Previous research suggests that in addition to being a characteristic of schizophrenia, neuromotor dysfunction also predates the onset of the syndrome. The research reported here was intended to examine further the neuromotor development of children with preschizophrenia traits. This study is part of a larger "archival-observational" project that uses childhood home movies to explore the develo...