Aortic pulse wave velocity (PWV) is an independent determinant of cardiovascular risk. Although aortic stiffening with age is well documented, the interaction between aging and regional aortic PWV is still a debated question. We measured global and regional PWV in the descending aorta of 56 healthy subjects aged 25-76 years using a one-dimensional, interleaved, Fourier velocity encoded pulse se...

Background: Diastolic retrograde flow in the descending aorta has been associated to the severity of aortic regurgitation; however, most of the parameters related to flow velocity are not validated with a reference imaging technique. Objective: The aim of this study was to assess the usefulness of diastolic retrograde flow in the descending thoracic aorta and the abdominal aorta in the quantifi...

Coarctation of the mid-thoracic aorata was surgically produced in mongrel dogs which were sacrificed from 4-12 wk after the operation. As compared to the findings in control animals, the sodium, chloride, and water content of the hypetensive portion of the coarcted thoracic aorta was significantly elevated, whereas the electrolyte and water content of the relatively normotensive portion of the ...

BACKGROUND Atherosclerosis is a progressive disease that causes vascular remodeling that can be positive or negative. The evolution of arterial wall thickening and changes in lumen size under current "standard of care" in different arterial beds is unclear. The purpose of this study was to examine arterial remodeling and progression/regression of atherosclerosis in aorta and carotid arteries of...

BACKGROUND Statins are not effective in reducing atherosclerotic plaques of the abdominal aorta, and accumulating evidence suggests that bisphosphonates have the potential to induce the regression of atherosclerotic plaques of the abdominal aorta. METHODS AND RESULTS A prospective, randomized, open-label, blinded-end-point trial involving 108 participants with hypercholesterolemia was conduct...

A 77-year-old woman who had undergone graft replacement of the descending aorta 18 years prior presented to our hospital complaining a cough with bloody sputum. She was diagnosed aortobronchial fistula by computed tomography. Thoracic endovascular aortic repair performed, and patient discharged from without any major complications. Postoperatively, sputum disappeared, tomography examination at ...

A 79-year-old hypertensive man with chronic type B aortic dissection (TBAD) came acute chest pain. CT revealed partially thrombosed aneurysmal dilatation of false lumen, compressing trachea and oesophagus (chronic complicated TBAD) the extremely tortuous descending thoracic aorta ([figures

ObjectiveThis study evaluated the efficacy of provisional extension to induce complete attachment (PETTICOAT) technique for type B and postoperative residual aortic dissections compared with conventional thoracic endovascular repair (TEVAR) technique.MethodsIn this retrospective study, we sequential morphologic changes in consecutive patients treated PETTICOAT between January 2016 December 2017...

This study investigated the effects of hypertension on regional aortic biomechanical and structural properties in three rat models of vascular calcification: the hypertensive Lewis polycystic kidney (LPK; n = 13) model of chronic kidney disease, spontaneously hypertensive rats (SHRs; n = 12), and calcification in normotensive Lewis rats induced by vitamin D3 and nicotine (VDN; n = 8). Lewis and...

This study investigated the effect of chlorpyrifos on thoracic aorta and on the level of NO in plasma and aorta. The effect of chlorpyrifos on thoracic aorta in organ bath was determined in 10 rats. Another 45 rats were assigned to 3 groups with 15 rats each: control group 1 received distilled water, control group 2 was given corn oil, and the last group was given 13.5 mg/kg chlorpyrifos dissol...