The case report on cotrimoxazole-induced pancreatitis by Versleijen et al. deals with the assessment of the probability that cotrimoxazole induced the acute pancreatitis: a causality assessment. In this editorial, we comment on this assessment from a clinical, pharmacological and epidemiological perspective. Moreover, the consequences of the results of the assessment are discussed.

1. The network topology is characterized in the language of graph theory (e.g. tree, 0-chain, 1-chain) [1] [2]. By this means, the set of steady-state fluxes can be parameterized explicitly. 2. A particular steady-state solution is selected. This steady-state solution is used to generate a nominal, stationary routing algorithm for the stochastic flow problem. 3. However, to ensure the network o...