Continuing the early w o rk of M e l a n d e r , O l s s o n and coworkers1 who studied the heterogeneous acid catalysed hydrogen exchange in thiophene, determina­ tions of the dedeuteration 2 and detritiation 3 rates of a number of substituted thiophenes in homogeneous con­ ditions were recently carried out. The relative rates are strongly dependent on the substitution in the thio­ phene ring....

The deposition of protein aggregates in various parts of our body gives rise to several devastating diseases, and the development of probes for the selective detection of aggregated proteins is crucial to advance our understanding of the pathogenesis underlying these diseases. LCPs (luminescent conjugated polythiophenes) are fluorescent probes that bind selectively to protein aggregates. The co...

We report a comparative X-ray diffraction study on three series of comb-like polymers with rigid backbones and layered morphologies [regio-regular poly(3-alkyl thiophenes), alkoxylated polyesters, alkoxylated polyphenylenevinylenes] highlighting the importance of the volume per methylene unit VCH2 in alkyl nanodomains for the overall packing state. We demonstrate that there is a large (≈30%) va...

We present a general strategy for obtaining large sulfur-containing polycyclic aromatics from thienyl precursors through iron(III) chloride mediated oxidative cyclizations. By placing thienyl moieties in close proximity to adjacent arenes, we have directed the oxidized intermediates into controlled cyclization pathways, effectively suppressing polymer formation. Utilizing these cyclized compoun...