background: apelin is a mitogenic peptide; it has functions in vessel formation and cell proliferation. in this study we aimed to evaluate the serum and tissue levels and local expression pattern of apelin in eutopic and ectopic endometrium from patients with and without endometriosis and to compare the proliferative and secretory phase differences. methods: thirty women with endometriosis and ...

Total láclatedehydrogenase levels and M-type subunits of this enzyme were greatly increased, compared with normal values, in hyperplastic endometrium. The levels of láclatedehydrogenase in 43 cases of hyperplastic endome trium were similar lo Ihose in 3 cases of carcinoma of ine endometrium. The findings suggest that a biochemical relationship exists between hyperplasia and carcinoma of endom...

Our studies demonstrate significantly lower expression of relaxin and its receptor in ectopic endometriotic tissues than their expression in eutopic endometrium and in endometrium from normal controls. These data suggest that in normal and eutopic endometrium, relaxin may exert a protective effect against endometriosis.

Cigarette smoke contains around 4000 chemical substances including free radicals and carcinogens, which are xenobiotic agents in the body, affecting the reproductive system. Purple sweet potatoes contain the color pigment anthocyanin. The purple color pigment (anthocyanin) in purple sweet potatoes is a beneficial antioxidant because it can react with free radicals that can cause damage in the b...

Endocrinologic and metabolic abnormalities in polycystic ovary syndrome (PCOS) may have complex effects on the endometrium, contributing to the infertility endometrial disorders observed women with this  syndrome. The consequences of PCOS on homeostasis pathophysiology not been comprehensively understood. This review provides an overview molecular mechanisms endometrial  function with this path...

diapause. Pafr protein was present in a membrane bound form in the glandular epithelium of the endometrium across all stages, analysis studies are in progress to determine any temporal changes in levels of expression. In vitro, paf production from the endometrium increases after diapause (Kojima et al., 1993). p53 expression assessed by RT-PCR, was detected in the endometrium across all stages ...

BACKGROUND Cell properties, such as attachment, adhesion and invasion, are important for the normal function of the endometrium. However, it is believed that the same properties may also be involved in the development of gynaecological diseases, such as endometriosis. Endometrial cells, shed by retrograde menstruation, may have an aberrant expression of molecules involved in these functions, le...

results the mean age at the time of diagnosis was 54 years (range, 28 - 74). cause-specific survival rates of the entire group were 92%, 87% and 82%, at two, three and five years, respectively. the five-year cause-specific survival rates for grades one, two and three were 98%, 88% and 68%, respectively. multivariate analysis revealed that age, depth of myometrial invasion, involvement of ovarie...

OBJECTIVES The objective of the study is comparing pathohistological picture and test results of the activity of the enzymes of the anti-oxidative protection -cytoplasmic super-oxide dismutase (CuZnSOD) from the blood and endometrium in the promotion of the progression or regression of the hyperplasia and endometrium carcinoma. MATERIALS AND METHODS The study has been carried out on 70 patien...

diapause. Pafr protein was present in a membrane bound form in the glandular epithelium of the endometrium across all stages, analysis studies are in progress to determine any temporal changes in levels of expression. In vitro, paf production from the endometrium increases after diapause (Kojima et al., 1993). p53 expression assessed by RT-PCR, was detected in the endometrium across all stages ...