نتایج جستجو برای: thiazolidine 4 ones
تعداد نتایج: 1407163 فیلتر نتایج به سال:
Series of 4H-3,1-benzoxazin-4-ones and 3H-quinazolin-4-ones with phenoxy-methyl substituents were rationally designed and easily synthesized via one-pot N-acylation/ring closure reactions of anthranilic acids with 2-phenoxyacetyl chlorides to yield the 4H-3,1-benzoxazin-4-ones, and subsequently substituted with amino derivatives to obtain the 3H-quinazolin-4-ones. The herbicidal evaluation was ...
We herein describe the rapid synthesis of a diverse set of dihydroquinazolin-4-ones and quinazolin-4-ones, their biological evaluation as thyroid stimulating hormone receptor (TSHR) agonists, and SAR analysis. Among the compounds screened, 8b was 60-fold more potent than the hit compound 1a, which was identified from a high throughput screen of over 73,000 compounds.
The characterization and design of this study new liquid crystals with a V shape compounds containing thiazolidine-2,4-dione 1,3-phenylene as core unite mesophase properties were reported. Preparation chloroacetic acid, water, thiourea to produce [I] in the presence strong hydrochloric acid. 4-hydreoxybenzaldehyde n-alkyl bromide reacted potassium hydroxide create n-alkoxy benzaldehyde., then c...
Abstract: Background: From the wide range of previous literature studies indicated that thiazolidinedione’s reacts with substituted benzaldehydes undergoes knoevenagel condensation gives respective arylidene derivatives. In our attempt all titled compounds were designed and developed by replacement furan- 2-aldehyde, so furan moiety was introduced in molecule. Materials Methods: 5-[(furan-2-yl)...
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