Background: Thiamin or vitamin b1 is a therapy that has been widely used in neurology cases such as alcohol-induced encephalopathy and neuropathy. the ability to penetrate blood brain barrier so it expected be an additional stroke cases. Stroke currently emergency case causes high mortality disability. Among because damage large areas of will cause release neurotransmitters glutamate which exci...

Body mass index (BMI) correlates with several anthropometric parameters including body adiposity. Comparisons of genetic and environmental factors have resulted in a heritability estimate for BMI of about 70%.Thiamin is a vitamin involved in energy metabolism and metabolic pathways for carbohydrates, amino acids, and fatty acids. This vitamin functions as a coenzyme for transketolase and th...

Results are presented on the rate of thiamin cleavage by sulphite in aqueous solutions as affected by temperature (20-700), pH (2.5-7.0), and variation of the concentration of either thiamin (1-20,UM) or sulphite (10-5000,UM as sulphur dioxide). Plots ofthe logarithmn ofpercentage ofresidual thiamin against time were found to be linear and cleavage thus was first-order with respect to thiamin. ...

In the early part of the rainy season in 1988, an outbreak of beriberi occurred in free-living adults in a relatively small area in the North Bank region of The Gambia. In 1995 we selected two compounds in a village called Chilla situated within the affected district to retrospectively examine dietary factors potentially contributing to the outbreak. There had previously been cases of beriberi ...

Genetic disorders of BCAA metabolism produce amino acidopathies and various forms of organic aciduria with severe clinical consequences. A metabolic block in the oxidative decarboxylation of BCAA caused by mutations in the mitochondrial branched-chain alpha-keto acid dehydrogenase complex (BCKDC) results in Maple Syrup Urine Disease (MSUD) or branched-chain ketoaciduria. There are presently fiv...

Genetic disorders of BCAA metabolism produce amino acidopathies and various forms of organic aciduria with severe clinical consequences. A metabolic block in the oxidative decarboxylation of BCAA caused by mutations in the mitochondrial branched-chain a-keto acid dehydrogenase complex (BCKDC) results in Maple Syrup Urine Disease (MSUD) or branched-chain ketoaciduria. There are presently five kn...

I. Three experiments involving sixty-two growing-finishing pigs from 28 to 90 kg bodyweight were conducted to investigate the effect of environmental temperature on the thiamin requirement of growing-finishing pigs. Three temperatures (zoo, 30' and 35") were used. 2. Under these experimental conditions, average daily weight gain indicated no effect of environmental temperature on thiamin requir...

Vitamin B1 (thiamin) is required in the metabolism of carbohydrates, lipids, proteins, and energetic metabolism within Krebs cycle. It has also an essential role in acetylcholine synthesis and neurotransmission.1 Thiamin deficiency can lead to various manifestations such as Gayet-Wernicke syndrome, wet beriberi with congestive heart failure, or dry beriberi with peripheral neuropathy. We report...

OBJECTIVE To investigate the impact of fortification by comparing food records and selected biochemical indicators of nutritional status pre- and post-fortification. DESIGN Mean intake from 24 h recalls (n 142) was compared with the Estimated Average Requirement (EAR) to determine the proportion with inadequate intake. In a subsample (n 34), diet and serum retinol, folate, ferritin and Zn wer...

Pyruvic acid is a normal intermediary of carbohydrate metabolism (1, 2). It has been previously demonstrated that thiamin, or more particularly thiamin pyrophosphate (cocarboxylase), is concerned in the normal catabolism of pyruvic acid (1). In Oriental beri-beri (3) and peripheral neuropathy in the alcohol addict (4)-both diseases associated with a deficiency of thiaminhyperpyruvemia does occu...