Treatment with radioactive isotopes has been the irst clinical application of Nuclear Medicine, when, in the early ‘40s, the Phosphorus-32 was used for polycythemia and some forms of leukemia [4,5] and subsequently the administration of iodine-131 was adopted for the therapy of thyroid disease [4,6]. Than nuclear medicine therapy has come a long and successful road, with the synthesis of many c...

Islet cell transplantation has recently emerged as a promising means to treat patients with type 1 diabetes. Despite significant success with the Edmonton protocol for intraportal naked islet transplantation (1), there is an active debate regarding whether or not the overall clinical success rates have met initial expectations (2,3). The next vital steps for improving islet cell transplantation...

A novel photo-crosslinkable nanogel is prepared from a biodegradable polymer template with intrinsic photoluminescence and high photostability. The fluorescent nanogels display excellent biodegradability and cytocompatibility owed to the facile synthesis scheme involving a solvent-and surfactant-free one-pot reaction, derived entirely from biocompatible monomers citric acid, maleic acid, L-cyst...

Introduction: Growing advances in nanotechnology have facilitated the applications of newly emerged nanomaterials in the field of biomedical/pharmaceutical sciences. Following this trend, the multifunctional nanoparticles (NPs) play a significant role in development of advanced drug delivery systems (DDSs) such as diapeutics/theranostics used for simultaneous diagnosis and therapy. Multifunctio...

Abstract Recent advances in inorganic nanomaterial-based theranostics enabled imaging-guided molecular targeting and drug delivery, various combinations of theranostic systems. The term “theranostics” is defined as diagnosis processed with therapy simultaneously a specific connection between diagnosis. nanomaterials, representatively carbon, metal, ceramic, semiconductor-based exhibit their uni...