The present study aimed to evaluate the protective effect of crocin on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rats. Forty male rats were randomly divided into sham, control (I/R injury) and three crocin-pretreated groups. To induce I/R lesions, the celiac artery was clamped for 30 min and then the clamp was removed to allow reperfusion for 3 h. Pretreated-rats re...

Background: We aimed at evaluating the toxicity effects of low (subtoxic) concentrations of silver nanoparticles (AgNP, 5-10 nm) in human hepatoblastoma (HepG2) cell line after and during a period of about one month. Methods: XTT and MTT assays were used to draw a dose-response curve IC50 (half maximal inhibitory concentration) value of the AgNP on HepG2 cells was calculated to be 2.75-3.0 mg/l...

Zinc is an essential mineral and accepted as a trace element in the animal nutrition and for its role in biological enzymatic pathways. This study aimed to investigate the effect of oral administration of zinc oxide nanoparticles (ZnONPs) on some of the antioxidant parameters of semen plasma, quantitative and qualitative properties of Arabic ram sperm in the non-breeding season. Twelve adult Ar...

The biopharmaceuticals market is constantly growing. Despite their advantages over the conventional drugs, have short biological half-lifes, which can be increased using liposomes. However, common bulk methods to produce biopharmaceuticals-loaded liposomes result in lost of encapsulation efficiency (E.E.), resulting an expensive process. Herein, a therapeutic enzyme proposed, glass-capillary mi...

Background: A sequence of time-dependent changes can affect the brainchr('39')s functional capacity. Aims: This study aimed at investigating the effects of forced aerobic exercise (FAE) versus the rosemary extract (RE) on the learning abilities and oxidative stress modulation in rats. Methods: Young and old rats received daily FAE and RE for 3 months. Using the passive avoidance (PA) test, we...

In this study, it was aimed to investigate the effects of salinity, which is an important environmental problem, in cultivation ornamental plants (such as zinnia) and irrigation with high salt water, especially on antioxidant defense mechanism. For purpose, two Zinnia species were irrigated by different concentrations saline water (50, 100, 150, 200 mM NaCl); salinity superoxide dismutase (SOD)...

Oxidative stress caused by various pollutants in water can be overcome different mechanisms aquatic organisms. Antioxidant enzymes play major role to minimize the hazardous effect of heavy metals fish. Superoxide dismutase is one antioxidant enzyme that converts superoxide radical into hydrogen peroxide (H2O2) and thus free radicals. Therefore, aim this research was evaluate activity (SOD) orga...

abstract     crop residues are well known for their chemical (allelopathic) effects on crops. the allelopathic potential of the aqueous extracts and chopped residual of sorghum (sorghum bicolor l.) on germination, seedling growth, relative water content, seedling dry weight, seedling length and antioxidant enzyme activity namely catalase (cat), peroxidase (pod) and superoxide dismutase (sod) of...

Materials and methods: Classical biochemical methods were used to determine plasma malondialdehyde (MDA), nitric oxide (NO), glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), and glutathione (GSH) levels. Enzyme-linked immunosorbent assay was used to determine plasma insulin levels and reverse transcriptasepolymerase chain reaction was used to determine the levels of ...

BACKGROUND: Cancer cachexia is the progressive loss of skeletal muscle protein that contributes significantly to cancer morbidity and mortality. Evidence of antioxidant attenuation and the presence of oxidised proteins in patients with cancer cachexia indicate a role for oxidative stress. The level of oxidative stress in tissues is determined by an imbalance between reactive oxygen species prod...