our ancestors without fear, worry and anxiety are not our ancestors, as organisms without defense systems were extinct. therefore, while behavior such as fear and anxiety are useful to prevent harm, the exaggerated form, that is, anxiety disorders, has more costs than benefits. likewise, while a panic attack is a normal and useful response in the face of life-threatening danger, a panic disorde...

Static analysers search for overapproximating proofs of safety commonly known as safety invariants. Fundamentally, such analysers summarise traces into sets of states, thus trading the ability to distinguish traces for computational tractability. Conversely, static bug finders (e.g. Bounded Model Checking) give evidence for the failure of an assertion in the form of a counterexample, which can ...

a r t i c l e i n f o The notion that people with higher income are more concerned about environmental problems is deeply entrenched in economics and some other disciplines. Studies have shown a positive income effect on the intention to pay for environmental improvement. Perception of environmental risk, however, follows a different pattern of variation. This paper demonstrates a negative inco...

Figure 1. Preoperative at 22 months old. Asymmetry of the cranium noted in which the cranium is growing superiorly and laterally on the left side of the patient's head due to a fused right lambdoid suture. Figure 2. Preoperative photograph showing a superior view demonstrating asymmetrical cranial growth of the left side of the patient's head due to a fused lambdoid suture on the right.

This article reviews the evidence for the danger model in the context of immune response to tumors and the insufficiency of the immune system to eliminate tumor growth. Despite their potential immunogenicity tumors do not induce significant immune responses which could destroy malignant cells. According to the danger model, the immune surveillance system fails to detect tumor antigens because t...