The cell-mediated immune system function was studied both in vitro and in vivo in 20 healthy women who had been taking combined oral contraceptives for an average of 2.8 years. All patients received intradermal injections of a 1/100 dilution of Candida albicans, a 1/100 dilution of mumps skin test antigen, a 1/10 dilution of tetanus toxoid fluid, and a 1/200 dilution of phytohemagglutinin-P. ...

Onchocerca volvulus infection has been associated with impaired cellular responses to parasite antigens, an impairment that may also extend to nonparasite antigens. To investigate the mechanism of this impaired immune response, the effect of concurrent O. volvulus infection on the immune response to tetanus toxoid (TT) following tetanus vaccination was studied. The proliferative, cytokine, and ...

To monitor progress toward maternal and neonatal tetanus elimination (MNTE) in Cambodia, we conducted a nationwide serosurvey of tetanus immunity in 2012. Multistage cluster sampling was used to select 2,154 women aged 15 to 39 years. Tetanus toxoid antibodies in serum samples were measured by gold-standard double-antigen enzyme-linked immunosorbent assay (DAE) and a novel multiplex bead assay ...

INTRODUCTION The association of Guillain-Barré syndrome with vaccination has been described in the literature; it is infrequent and controversial. An association with swine influenza, influenza, hepatitis and tetanus vaccination has been documented in few case reports. CASE PRESENTATION A 40-year-old Caucasian man sustained a small right temporal epidural hematoma and nondisplaced right skull...

BACKGROUND In spite of the clear-cut guidelines regarding tetanus immunization, we have observed that tetanus toxoid injection is often given after injury without considering previous immunization status. One of the reasons for this could be that the doctors themselves are not aware of the correct immunization schedules against tetanus. AIMS 1. To assess the knowledge about tetanus immunizati...

Sir, I thought your readers may be interested in the management of a recent case of tetanus which occurred at this hospital. A 63-year-old lady presented to the Accident and Emergency Department soon after laceration to her right leg, caused by a sheet of glass taken from a dismantled greenhouse in her garden. A 'V'-shaped flap, 4 cm each limb, an apparently clean and subcutaneous wound, was si...

Human T cell hybridomas were produced by fusing the hypoxanthine phosphoribosyltransferase-deficient line of the human T cell lymphoma Jurkat with a continuous line of normal human T cells specific for tetanus toxoid (TeT). The hybridomas were selected for their ability to produce interleukin 2 after exposure to TeT on semiautologous monocytes and for their ability to bind to TeT-pulsed semiaut...

Objective: Tetanus remains a major public health problem in the developing countries despite availability of active immunization and passive since long. Non-sterile ear piercing instrumentation pose constant threat tetanus associated with morbidity mortality. Study Design: Retrospective Cross-sectional study. Setting: Department Pediatric, Bahawal Victoria Hospital Bahawalpur. Period: June 2019...

Tetanus is a vaccine-preventable disease and remains an important cause of under five morbidity and mortality, especially in the developing countries. Tetanus is considered as a failure of public health system. Here the clinical course of neonatal tetanus of eighteen days old female baby who was presented to Daror health centre with complaints of refusal to take feeding, inability to open her m...