Arginine/serine protein kinases constitute a novel class of enzymes that can modify arginine/serine (RS) dipeptide motifs. SR splicing factors that are essential for pre-mRNA splicing are among the best characterized proteins that contain RS domains. TwoSRprotein-specifickinases, SRPK1 and SRPK2, have been considered as highly specific for the phosphorylation of these proteins, thereby contribu...

Within the mammalian testis, specialized tight junctions between somatic Sertoli cells create basal and apical polarity within the cells, restrict movement of molecules between cells, and separate the seminiferous epithelium into basal and adluminal compartments. These tight junctions form the basis of the blood-testis barrier, a structure whose function and dynamic regulation is poorly underst...

PURPOSE Retractile testis is considered to be a variant of normal testis in prepubertal boys. There is no agreed-upon management of retractile testis. The aim of this study was to provide data on the long-term outcomes of patients with retractile testis. MATERIALS AND METHODS This study retrospectively reviewed the medical record of 43 boys who were referred for suspected undescended or retra...

The testis is the special male gonad responsible for spermatogenesis and steroidogenesis with complex gene expressions. Characterizing and comparing the testis-specific genes in different species can reveal key genes related to testis specific functions and provide supplementary information for study of human testis function. We screened testis-specific genes from Unigene libraries, total 317, ...

Abstract Autoimmune diseases play a critical role in the progression of infertility both sexes and their severity has been reported to increase with age. However, few reports have discussed effect on morphological features testis. Therefore, we compared alterations testes autoimmune model mice (MRL/MpJ-Fas lpr ) control strain (MRL/MpJ) those background (C57BL/6N) at 3 6 months. Furthermore, an...

Erkeklerde spermatogenezin normal şekilde gerçekleşebilmesi için testislerin karın boşluğu dışında, vücuttan 2-3°C düşük sıcaklıkta skrotum adı verilen kese içerisine inmeleri gerekmektedir. Testis iniş mekanizması türler arasında farklılık göstermekle birlikte, intrabdominal seviyeden skrotuma hormonal ve mekanik etkilere bağlı olarak transabdominal inguinoskrotal evreler sonunda gerçekleşmekt...

introduction: undescended testis is a common problem in children. cryptorchid testis is frequently accompanied by gross morphologic changes with regard to the size and shape of the testis, various degree of detachment between the epididymis and testis. we assessed the epididymal anomalies and patency of process vaginalis in boys with udt.   material &method;: it is a prospective study which was...