BACKGROUND Adverse drug reactions (ADRs) are an important cause of harm in children. Current data are incomplete due to methodological differences between studies: only half of all studies provide drug data, incidence rates vary (0.6% to 16.8%) and very few studies provide data on causality, severity and risk factors of pediatric ADRs. We aimed to determine the incidence of ADRs in hospitalized...

With the introduction of penicillin treatment for early syphilis, the prognosis for this infection has significantly changed, and it is to be expected that late syphilitic manifestations will become increasingly rare. Even if the period of latency so far allowed for the development of late manifestations is at present too short for a final assessment of penicillin treatment, the action of penic...

BACKGROUND Hospital admissions due to adverse drug events (ADEs) are expensive, and many may be preventable, yet few institutions have ongoing surveillance for these events. OBJECTIVE To evaluate the use of a computer-based ADE monitor to identify admissions due to ADEs and to measure the associated costs. DESIGN Prospective cohort study in one tertiary care hospital. PARTICIPANTS All pat...

BACKGROUND The increasing demand on hospitalisation, either due to elective activity from the waiting lists or due to emergency admissions coming from the Emergency Department (ED), requires looking for strategies that lead to effective bed management. The aim of this study was to evaluate the effectiveness of a surgery admission unit for major elective surgery patients who were admitted for sa...

BACKGROUND Head and neck oncologic surgery is a time-consuming specialty that requires extensive resources and manpower. Case mix index (CMI) is used in evaluating the complexity and economic impact of surgeons. Head and neck oncologic surgeons generate significant revenue for hospitals, yet compensation is relatively low. METHODS Retrospective review of a tertiary hospital's case mix data fo...

OBJECTIVES To identify system-based factors contributing to Emergency Department (ED) admissions of children with diabetic ketoacidosis (DKA) and related complications with emphasis on parental and physician awareness and prereferral management. MATERIALS AND METHODS A prospective observational root cause analysis study of all consecutive admissions of children with DKA to pediatric ED of a t...

All children attending the Aseer Central Hospital (the only tertiary hospital in Aseer region, southwestern Saudi Arabia) with lobar pneumonia (315 children) during the period from January 1987 to December 1999 were studied. Out of these, forty-five children were found to have ghee lipoid pneumonia (diagnosed by oil red 0 stain). All of them were given oral and/or nasal administration of ghee f...

A hospitalist-run acute medical unit (AMU) opened at a tertiary care hospital on August 2015 for the first time in Korea. Patients visiting the emergency department (ED) with acute medical problems are admitted to the AMU. They stay in that unit for less than 72 hours and are discharged or transferred to specialty wards if longer treatment is necessary. We reviewed 19,450 medical admissions thr...

BACKGROUND Our hypothesis was that telehealth in combination with an optimised care program coordinated amongst care professionals in primary, secondary and tertiary care can achieve beneficial outcomes in heart failure. The objective was to evaluate the clinical effects of introduction of telehealth in an optimised care program in a community hospital in the north of the Netherlands. METHODS...

OBJECTIVES To evaluate the clinical effectiveness, safety, and cost of dexmedetomidine for the treatment of agitated delirium refractory to haloperidol in nonintubated critically ill patients. DESIGN Nonrandomized, controlled trial. SETTING Intensive care department of a tertiary care nonprofit hospital. PATIENTS All consecutive admissions to a medical-surgical ICU with a diagnosis of agi...