We read with interest the article by Gafton et al published in 2012. The authors illustrated the use of a dual-phase CT protocol for the enhancement characterization of parathyroid lesions and suggested the elimination of precontrast and delayed scan phases from 4D CT to reduce radiation exposure. In this letter, we describe the alternative approach of our institution to 4D CT. Our modified 4D ...

We report a case of intrathyroidal and ectopic parathyroid hyperplasia in a 47-year-old female patient with secondary hyperparathyroidism. During evaluation for end stage renal disease, hypercalcemia and hyperparathyroidism were detected in laboratory exam and thyroid nodules were found in computed tomography, and thyroid ultrasonography. In subsequent dual-phase technetium-99m methoxyisobutrli...

Introduction: We aimed to investigate the effect of right bundle branch block (RBBB) on perfusion and functional parameters in dipyridamole stress/rest Tc99m-MIBI gated myocardial perfusion SPECT (GSPECT) which may be helpful in interpretation of myocardial perfusion imaging. Methods: We studied 73 patients with low pre-test likelihood of coronary artery disease in two groups: 38 patients with ...

BACKGROUND/AIM Primary hyperparathyroidism (pHPT) is an endocrine disease with the third highest incidence of all endocrine disorders after diabetes mellitus and hyperthyroidism. pHPT is typically caused by a solitary parathyroid adenoma, less frequently by multiple parathyroid gland disease (MGD) and rarely by parathyroid carcinoma. Secondary hyperparatyroidism (sHPT) is a common complication ...

PURPOSE Imaging with (99m)Tc-sestamibi ((99m)Tc-MIBI) has been used to assess 170-kDa P-glycoprotein (P-gp) expression and predict chemotherapy responses in several types of malignancy, such as breast and lung cancers. The purpose of this study was to evaluate the relationship between (99m)Tc-MIBI accumulation in tumors and sensitivity to chemotherapy in gastric cancer patients. EXPERIMENTAL ...

Osteitis fibrosa cystica is the classic patognomonic form of skeletal disease in hyperparathyroidism that characterizes with decreased cortical bone thickness compared to increased cancellous bone. We present a case of 52-year old female patient with osteolysis of the left calf on radiographic images. The bone scan detected multiple focal pathological accumulations in the skull, left tibia, bot...

INTRODUCTION Preoperative accurate localization of enlarged adenoma (s) in primary hyperparathyroidism (PHPT) is a vital necessity. Technetium 99m sestamibi scanning is commonly used with reported acceptable sensitivities; however, false negative scan studies remain a problem. Determining effective factors on the sensitivity of the scan might improve the diagnostic value of the study by selecti...

Received 8/30/2000; accepted 9/5/2000. For correspondence or reprints contact: Chia-Hung Kao, M.D., Department of Nuclear Medicine, Taichung Veterans General Hospital, 160, Sec. 3, Taichung Harbor Road, Taichung 407, Taiwan, R.O.C. Tel: (886)4-23741349, FAX: (886)4-23741348, E-Mail: [email protected] Tc-MIBI scanning has become the preferred mode to detect and localize parathyroid adenom...

UNLABELLED Parathyroid scintigraphy and high-resolution ultrasonography are frequently used as preoperative localization procedures in primary hyperparathyroidism. However, when thyroid disease coexists, their diagnostic accuracy is probably abated. DESIGN 56 patients with primary hyperparathyroidism were prospectively evaluated with parathyroid scintigraphy (with either thallium or technetiu...