نتایج جستجو برای: targeted cancer therapy

تعداد نتایج: 1553027  

Journal: :Biochemistry & Pharmacology: Open Access 2015

Journal: :Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 2010

Journal: :Molecular Therapy - Nucleic Acids 2017

Journal: :Japanese Journal of Clinical Oncology 2017

Journal: :Visualized cancer medicine 2023

Integrins represent ideal targets for molecular imaging and targeted therapy of cancer their role in has been reviewed extensively elsewhere. Except αVβ3 αVβ5, the remaining integrins were not systematically considered tested as potential therapeutic targets. In recent years, studies on integrin α6 a target are increasing, due to highly expressed several cancers, expression associated with poor...

2012
Lindsay Riley Hua Zhou Kenneth Lange Janet S. Sinsheimer Mary E Sehl

INTRODUCTION Trastuzumab dramatically improves survival in breast cancer patients whose tumor overexpresses HER2. A subpopulation of cells in human breast tumors has been identified with characteristics of cancer stem cells. These breast cancer stem-like cells (BCSCs) rely on HER2 signaling for self-renewal, suggesting that HER2-targeted therapy targets BCSCs even when the bulk of the tumor doe...

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