The aim of the study was to jointly analyze temperature-induced changes in low-threshold single motor unit twitch torque and action potential properties. Joint torque, multichannel surface, and intramuscular electromyographic signals were recorded from the tibialis anterior muscle of 12 subjects who were instructed to identify the activity of a target motor unit using intramuscular electromyogr...

BACKGROUND The objective of this study was to investigate the relationship between different target levels of glucose and the clinical outcomes of patients undergoing cardiac surgery with cardiopulmonary bypass. METHODS We designed a prospective study in a university hospital where 109 consecutive patients were enrolled during a six-month period. All patients were scheduled for open-heart sur...

We introduce a variant of the classic sealed-bid unit-demand auction in which each item has an associated put option. The put option of an item is held by the seller of the item, and gives the holder the right to sell the item to a specified target bidder at a specified strike price, regardless of market conditions. Unexercised put options expire when the auction terminates. In keeping with the...

Posit is a numerical representation that especially focused on deep neural networks (DNNs). However, specific register called quire necessary for posit multiply-accumulate (MAC) unit to ensure the calculation accuracy. In this paper, we proposed based MAC can optimize size according target applications. We also develop DNN library explore of unit. Experimental result with ResNet-9 showed achiev...

it was shown that permethrin resistance in adult anopheles stephensi is due to at least three separate mechanisms. cytochrome p-450s and esterases are responsible for two-thirds of the 8-fold enhanced tolerance of the dub-apr resistant strain as compared with a sensitive strain, ind-s. it was postulated that target site insensitivity is also involved. to test this hypothesis, we conducted a neu...

In this paper, we present a method to take into account visual information during the selection process in an acoustic-visual synthesizer. The acoustic-visual speech synthesizer is based on the selection and concatenation of synchronous bimodal diphone units i.e., speech signal and 3D facial movements of the speaker’s face. The visual speech information is acquired using a stereovision techniqu...

OBJECTIVE To study the pharmacokinetics of micafungin in intensive care patients and assess pharmacokinetic (PK) target attainment for various dosing strategies. METHODS Micafungin PK data from 20 intensive care unit patients were available. A population-PK model was developed. Various dosing regimens were simulated: licensed regimens (I) 100 mg daily; (II) 100 mg daily with 200 mg from day 5...

*Department of Pain Therapeutics and Animal Welfare Group, Discovery Biology, Pfizer Global Research and Development, Sandwich Laboratories, B500 IPC 351, Sandwich, Kent CT13 9NJ, United Kingdom; §Department of Molecular Sciences, Pfizer Global Research and Development, Ann Arbor, MI 48105; and ¶Laboratory of Cellular and Molecular Neuroscience, Department of Pharmacology, University College Lo...

The major computational challenge of multi-target tracking in clutter is solving the report-to-track association problem. Multiple hypothesis tracking (MHT) [4] is an approximate solution that tries to limit the combinatorial complexity of assignment data to models in multiple frames. MHT processing and memory requirements grow exponentially with the increased number of frames used to resolve t...